BACKGROUND We hypothesised that myocardial deformation determined with magnetic resonance imaging (MRI) will detect myocardial scar. METHODS Displacement Encoding with Stimulated Echoes (DENSE) was used to calculate left ventricular strain in 125 patients (29 women and 96 men) with suspected coronary artery disease. The patients also underwent cine imaging and late gadolinium enhancement. 57 ...

The recently developed Reference Point Indentation (RPI) allows the measurements of bone properties at the tissue level in vivo. The goal of this study was to compare the local anisotropic behaviour of bovine plexiform bone measured with depth sensing micro-indentation tests and with RPI. Fifteen plexiform bone specimens were extracted from a bovine femur and polished down to 0.05µm alumina pas...

The highly organized structure and composition of the annulus fibrosus provides the tissue with mechanical behaviors that include anisotropy and nonlinearity. Mathematical models are necessary to interpret and elucidate the meaning of directly measured mechanical properties and to understand the structure-function relationships of the tissue components, namely, the fibers and extrafibrillar mat...

A series of supersonic wind tunnel tests on an ogive-cylinder body were performed to investigate the pressure distribution, the boundary layer profiles, and the flow visualization at various angles of attack. All tests were conducted in the trisonic wind tunnel of the Imam Hossein University. The theoretical shock angle at different model positions compared well with those we obtained via Schi...

In this article, thermo-elastic-behavior of a thick-walled cylinder made from a polystyrene nanocomposite reinforced with functionally graded (FG) single-walled carbon nanotubes (SWCNTs) was carried out in radial direction while subjected to a steady state thermal field. The SWCNTs were assumed aligned, straight with infinite length and a uniform layout. Two types of variations in the volume fr...

Residual stresses are present in a number of soft tissues. In the case of arterial walls they are supposed to be responsible for a smoothed circumferential stress gradient in radial direction. In the recent past, several publications dealt with residual stresses based on a multiplicative split of the deformation gradient using a cylindrical coordinate system, cf. for example [1], [2] and [3] an...

The collagen microstructure of the peripheral cornea is important in stabilizing corneal curvature and refractive status. However, the manner in which the predominantly orthogonal collagen fibrils of the central cornea integrate with the circumferential limbal collagen is unknown. We used microfocus wide-angle x-ray scattering to quantify the relative proportion and orientation of collagen fibr...

Understanding the passive mechanical properties of infarcted tissue at different healing stages is essential to explore the emerging biomaterial injection-based therapy for myocardial infarction (MI). Although rats have been widely used as animal models in such investigations, the data in literature that quantify the passive mechanical properties of rat heart infarcts is very limited. MI was in...

Static elastic properties were studied in isolated segments of the left coronary circumflex artery (LCCA) and the right common carotid artery (CA) from 14 dogs at in-vivo values of pressure and length. A microscope with a Filar micrometer was used to measure radius and length. From these data it was possible to study the pressure-radius relationship and compute various anisotropic elastic modul...