background and purpose: chronic granulomatous disease (cgd) is an inherited disorder of the nicotinamide adenine dinucleotide phosphate (nadph) oxidase complex. this disorder results in recurrent life-threatening bacterial and fungal infections. aspergillus species are the most common fungal infections in these patients. case report: herein, we present a case of fungal infection in a girl with ...

background: acute fulminant fungal sinusitis is a rapidly progressive disease with high mortality (50-80%) and occurring with increasing frequency in patients with acute leukemia. the purpose of the present study was early diagnosis of this le­thal infection. methods: in a cross-sectional study, 142 patients with hematological malignancies were studied immediately by initiation of chemotherapy ...

Mucormycosis is a rare opportunistic fungal infection that occurs in certain immunocompromised patients. We present 2 cases of invasive mucormycosis due to Rhizopus spp. in patients with chronic granulomatous disease (CGD) and discuss their clinical presentation, management challenges, and outcomes.

Chronic granulomatous disease (CGD) is characterized by a defect in phagocytic cells that lead to recurrent bacterial and fungal infections. The etiology of most common fungal infections in CGD are Aspergillus species. Aspergillus nidulans is one of several species of Aspergillus with low pathogenicity. However, it was reported to cause fatal invasive Aspergillosis in patients with CGD. Here we...

Cerebral angioinvasion is a fatal complication of disseminated aspergillosis and has been rarely described in diabetic population in the absence of ketoacidosis. We present a case of invasive fungal sinusitis in a 79 year old diabetic man who presented with chronic frontal headaches. Despite appropriate medical and surgical treatment, the disease progressed and the patient eventually succumbed ...

Allergic fungal sinusitis (AFS) is a benign, extramucosal, noninvasive fungal sinus disease representing an allergic/hypersensitivity response to extramucosal fungal pathogens in the sinus [1]. It occurs mainly in immunocompetent patients, in contrast to invasive fungal diseases that usually involve an immunocompromised host. The incidence of AFS in patients affected by chronic rhinosinusitis a...