Chronic Urticaria (CU) is a skin disorder characterized by wheal and flare with duration of more than 6 weeks affecting 1%-2% the population (more common in women). Thirty to 35% cases CU have angioedema [1]. The etiology chronic spontaneous urticarial not usually clear, 40%-50% are idiopathic 30%-40% autoimmune [2, 3]. Quality life disturbed which has direct relation severity [4].

Urticaria is a common condition that occurs in both children and adults. Most cases have no specific allergic trigger and the aetiology of urticaria remains idiopathic and occasionally spontaneous in nature. Inappropriate advice such as avoidance of foods (milk, egg, prawn, and brinjal) is common place in certain sections of India mostly by nonspecialists that should not be routinely recommende...

Skin tests with autologous serum elicit an immediate wheal-and-flare response in about 30-50% of chronic idiopathic urticaria subjects, suggesting that an autoimmune mechanism might be involved in the pathogenesis of this disease. The aim of the present work, involving 68 subjects with chronic idiopathic urticaria, was to distinguish between the serum-positive and serum-negative cases and highl...

We report a case of a 45 year old woman which fulfilled the criteria of chronic urticaria (remitting and relapsing bouts of erythematous and pruriginuos lesions without angioedema, lasted four months). Cutaneous manifestations were not related to a specific inducing factor, had no benefit from antihystamine and steroid drugs and were associated sometimes with mild gastroentric disorders. Patien...

Abstract Purpose of review Urticaria is a frequent disorder that can present with erythema, edema, and pruritus involving the skin mucous membranes. Early diagnosis proper management urticaria according to type (i.e., acute vs chronic) utmost importance reduce burden disease prevent psychosocial comorbidities. In this review, we aim summarize chronic emphasis on differences. Recent findings Aut...

BACKGROUND Though autoimmune phenomena have been regularly associated with chronic urticaria in adults, data in children are sparse. AIM To describe our experience with children and adolescents with chronic urticaria and autoimmunity. METHODS AND RESULTS Of 187 patients referred for evaluation of chronic urticaria during a 7.5 year period, eight (4.3%), all females aged 7-17 years, had incr...

Coagulation activation has been demonstrated in two prototypic autoimmune skin diseases, chronic autoimmune urticaria and bullous pemphigoid, but only the latter is associated with increased thrombotic risk. Two markers of coagulation activation (prothrombin fragment F1+2 and fibrin fragment D-dimer) were measured by immunoenzymatic methods in plasma samples from 30 patients with active chronic...

Urticaria is among the most common skin diseases. It can be acute, chronic, mediated by a physical stimulus, or related to contact with an urticant. Some cases result from an underlying small vessel vasculitis. Our understanding of this condition is continuously expanding, and autoimmune mechanisms are now recognized as a cause of chronic urticaria. A search of the PubMed database (US National ...

BACKGROUND Chronic urticaria can be the initial clinical presentation of a number of different diseases. The objective of the present study was to report the associated diseases during a ten-year clinical-laboratory follow-up in patients with an initial diagnosis of chronic spontaneous urticaria (CSU) of unknown cause. METHODS A prospective, longitudinal cohort study with a ten-year clinical-...

AIM The drugs of choice in the treatment of urticaria in children are H1-antihistamines. The aim of the study was to evaluate children with urticaria and define risk factors for requirement of high-dose H1-antihistamines in children with urticaria. MATERIAL AND METHODS The medical data of children who were diagnosed as having urticaria admitted to our outpatient clinic between January 2014 an...