نتایج جستجو برای: chromanone
تعداد نتایج: 76 فیلتر نتایج به سال:
On the basis of recently reported abyssinone II and olympicin A, a series of chemically modified flavonoid phytochemicals were synthesized and evaluated against Mycobacterium tuberculosis and a panel of Gram-positive and -negative bacterial pathogens. Some of the synthesized compounds exhibited good antibacterial activities against Gram-positive pathogens including methicillin resistant Staphyl...
In the racemic title compound, C16H14O3, the ring of the 4-hy-droxy-benzyl substituent group forms a dihedral angle of 80.12 (12)° with the benzene ring of the chromanone system. Two C atoms of the pyran-one ring and the H atoms on the benzyl α-C atom are disordered over two sites, with site-occupation factors of 0.818 (8) and 0.182 (8). The crystal structure is stabilized by O-H⋯O hydrogen bon...
A novel family of 3-((4-oxo-4H-chromen-3-yl)methyl)-4H-chromen-4-one (bis-chromone) derivatives were designed, synthesized and studied for their anti-cancer activity using the XTT assay for the growth inhibition against various human cancer cells. Among them, 3-((5-(cyclohexylmethoxy)-4-oxo-4H-chromen-3-yl)methyl)-7-methoxy-4H-chromen-4-one and 3-((5-(cyclohexylmethoxy)-4-oxo-4H-chromen-3-yl)me...
We have identified peroxyl radicals as key targets to monitor in our quest to reconcile the chemistry and biology of reactive oxygen species (ROS). In this context, we pioneered the development of lipophilic fluorogenic antioxidants for the spatiotemporal imaging of lipid peroxyl radicals in the membrane of live cells [1]. Our strategy involves preparing receptor-reporter probes that mimic the ...
The endemic African genus Eucomis (Hyacinthaceae) has long been one of the most highly regarded sources of ethnomedicines in southern Africa, attracting the attentions of toxicologists, pharmacologists and phytochemists. This chapter reviews the ethnobotany of this small group of fourteen described taxa (ten species), and the known phytochemistry. Six taxa (five species) have been recorded used...
A synthetic approach accessing the pestalotiopsones, fungal chromones possessing a rare skeletal subtype, is reported for the first time. The synthesis of pestalotiopsone A (1) has been achieved in 7 linear steps (28%), from commercially available 3,5-dimethoxybenzoic acid and subsequently the first syntheses of pestalotiopsone B (2), C (3) and F (4) were performed utilising this chemistry. The...
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