Objective(s): Currently, the development of nanoparticles for the stabilization and targeted delivery of cardiac drugs has gained significance. The present study aimed to develop nontoxic nanoparticles based on chitosan-hyaluronic acid (HA), encapsulate dinitrosyl iron complexes (DNICs, donors NO) into the nanoparticles to increase the stability and effectiveness of their action, and assess the...

Lung cancer is one of the malignant tumors with highest mortality rate, and detection its tumor marker carcinoma antigen 125 (CA125) significant. Here, an electrochemical immunoassay for CA125 was described. Nitrogen-doped reduced graphene oxide (N-rGO), carboxylated multi-walled carbon nanotubes (CMWCNTs) gold nanoparticles (AuNPs) were applied to co-modify glassy electrode (GCE), after incuba...

Gold nanoparticles (AuNPs) had been synthesized with various molarities and weights of reducing agent, monosodium glutamate (MSG), and stabilizer chitosan, respectively. The significance of chitosan as stabilizer was distinguished through transmission electron microscopy (TEM) images and UV-Vis absorption spectra in which the interparticles distance increases whilst retaining the surface plasmo...

Herein we report the covalent grafting of chitosan on graphene oxide (GO) followed by a simple approach for anchoring silver (AgNPs) and gold (AuNPs) nanoparticles onto a chitosan grafted graphene oxide surface by a NaBH4 reduction method. Catalytic activity of prepared heterogeneous GO grafted chitosan stabilized silver and gold nanocatalysts (GO-Chit-Ag/AuNPs) was explored for the reduction o...

background: curcumin as a yellow natural compound extracted from turmeric root is known it as an antibacterial agent. one of the nanoparticles ability is to decrease the defects of usual drug delivery systems. chitosan is a low toxic, biodegradable, biocompatible and safe polymer which is used in production of nanoparticles. nanoparticles like chitosan-tripolyphosphate (tpp) are able to increas...

in this work, copper oxide nanoparticles have been synthesized via extractive rosmarinus officinalis leaves by simple and economic co-precipitation method at ambient conditions which it has used (ch3coo)2cu+h2o individually as cu sources. it was found that uniform copper oxide nanoparticles have been successfully produced at various temperature, namely 400, 600, and 800 0c. powder x-ray diffrac...

Nitric oxide (NO) is involved in several physiological processes, such as the control of vascular tone, the immune response and the wound healing process. Thus, there is a great interest in the development of NO-releasing drugs and in matrices which are able to stabilize and release NO locally in different tissues. Thiols, such as glutathione (GSH), are ready nitrosated to form the NO donors S-...

an innovative method based on the membrane bioreactor (mbr) technology was developed as a potential remedy for the water shortage. mbrs attracted much attention in the field of wastewater treatment and reuse. it is reported from many researchers that membrane bioreactor technology is feasible and an efficient method for the treatment of wastewater. however, mbrs are faced to membrane fouling whic...