We report a case of an isolated plexiform neurofibroma occurring in a patient with myasthenia gravis. A 48-year-old man presented with asymptomatic skin-colored nodules on the tip of his 4th finger. Microscopically, a plexiform neurofibroma was identified located in the dermis that appeared to originate from small superficial nerves. He had a 20-year history of treated myasthenia gravis; otherw...

INTRODUCTION Myasthenia gravis is a commonly undiagnosed condition in the elderly. Statin medications can cause weakness and are linked to the development and deterioration of several autoimmune conditions, including myasthenia gravis. CASE PRESENTATION We report the case of a 60-year-old Caucasian man who presented with acute onset of dysarthria and dysphagia initially attributed to a brain ...

Myasthenia gravis is a rare long-term neurological condition that is characterised by fluctuating skeletal muscle weakness and fatigue, as well as respiratory difficulties. It is both an acquired autoimmune disease and a chronic neuromuscular disorder. Because of its rarity, myasthenia gravis is relatively unknown and may be unfamiliar to many nurses. While there are various types of myasthenia...

INTRODUCTION Approximately ten to fifteen percent of patients with myasthenia gravis are found to have a thymoma, and twenty to twenty-five percent of patients with thymoma have myasthenia gravis. Thymomatous myasthenia gravis tends to have a difficult clinical course and poor prognosis. CASE PRESENTATION We report two cases (one patient of Asian ethnicity and the other of Caucasian ethnicity...

INTRODUCTION Graves' disease and myasthenia gravis are both auto-immune diseases and the coexistence of these two diseases is rare but well recognized. Myasthenia gravis is more frequent in patients with thyroid disease. CASE PRESENTATION Here we present a case of 28-year-old male patient having Auto-immune thyroid disease (Graves' disease) with concomitant myasthenia gravis. CONCLUSION In ...

ROWLAND, L.P., HOEFER, P.F.A., ARANOW, H., JR. & MERRITr, H.H. (1956) Fatalities in myasthenia gravis. Neurology (Minneap.), 6, 307. SAHAY, B.M., BLENDIS, L.M. & GREENE, R. (1965) Relation between myasthenia gravis and thyroid disease. Brit. med. J. i, 762. SIMPSON, J.A. (1960) Myasthenia gravis: a new hypothesis. Scott. med. J. 5, 419. SIMPSON, J.A. (1964) Immunological disturbances in myasthe...

The history of the development of knowledge of myasthenia gravis is reviewed. Clinical profiles of the immune and non-immune mediated forms of myasthenia are discussed. The current theory of pathogenesis is reviewed. Tests used to diagnose myasthenia gravis, and their comparative diagnostic yields are presented. Past and current modalities of treatment are reviewed. Future therapeutic stra...

Myasthenia gravis is an autoimmune disorder caused by autoantibodies against the nicotinic acetylcholine receptor on the postsynaptic membrane at the neuromuscular junction and characterised by weakness and fatigability of the voluntary muscles. It has a bimodal peak of incidence with first peak in the third decade and the second peak in the sixth decade. It is probably underdiagnosed in the ve...

BACKGROUND Myasthenia gravis is a disorder of neuromuscular transmission associated with autoantibodies against the nicotinic acetylcholine receptor. We have previously developed a customized protein macroarray comprising 1827 potential human autoantigens, which permitted to discriminate sera of patients with different cancers from sera of healthy controls, but has not yet been evaluated in ant...

BACKGROUND Generalized myasthenia gravis will develop in more than 50% of patients who present with ocular myasthenia gravis, typically within 2 years. The optimal treatment of ocular myasthenia gravis, including the use of corticosteroids, remains controversial. In addition, the prevalence of thymoma and the optimal performance of the edrophonium chloride test for ocular myasthenia remain unkn...