Human islet amyloid polypeptide (hIAPP) deposit is the hallmark of type 2 diabetes pathology. Here, we report that apo-cyclen, attached to a specific hIAPP recognition motif (NYGAIL), captured copper ions and became proteolytically active. This cyclen-NYGAIL-copper complex was able to interfere with hIAPP aggregation and cleave hIAPP. These activities rescued INS-1 cells from hIAPP induced cyto...

Achaemenothrombium dariusi Saboori, Wohltmann & Hakimitabar sp. nov. (Acari, Prostigmata: Trombidioidea) is described and illustrated from larvae ectoparasitic on Euxoafallax (Eversmann) (Lepidoptera: Noctuidae) from Sirch and Cheshmeh Bondar, Kerman province, Iran. It is the third species of this genus, which is recorded only from Iran. The status of this small family is discussed and a key to...

This contribution analyzes water chemical data for the Choapa basin, North Central Chile, for the period 1980-2004. The parameters considered are As, Cu Fe, pH, EC, SO₄⁻², Cl⁻¹, and HCO[Formula: see text], from samples taken in nine monitoring stations throughout the basin. Results show rather moderate contents of As, Cu, and Fe, with the exception of the Cuncumén River and the Aucó creek, expl...

sarcheshmeh porphyry copper deposit is located 65 km southwest of rafsanjan in kerman province. the sarcheshmeh deposit belongs to the southeastern part of urumieh-dokhtar magmatic assemblage (i.e., dehaj-sarduyeh zone). intrusion of sarcheshmeh granodiorite stock in faulted and thrusted early-tertiary volcano-sedimentary deposits, led to mineralization in miocene. in this research, the mass ch...

Pulsed electrolysis of copper has been systematically investigated by electrodepositing copper from a copper sulfate bath. Pulse duty cycles of 5 to 80 percent, at frequencies from 10 to 100 Hz with current densities ranging from 2.5 to 7.5 A/dm2 were employed. The appearance of Hull Cell panels with both direct current and pulsed current was recorded. The influence of pulsed current on current...

Scientists from the U.S. Geological Survey are evaluating the potential for undiscovered sulfide deposits containing varying amounts of nickel, copper, platinumgroup metals, and cobalt in the Lake Superior region as part of an ongoing effort to assess the mineral potential of the United States. Similarities between rocks of the Midcontinent rift and rocks that host the Voisey Bay nickel-copper-...