It was investigated whether Escherichia coli cultured in a glucose-limited chemostat is able to grow with a series of sugars whose utilization is normally repressed during batch growth with glucose. Cells growing at dilution rates of 0.2, 0.3 and 0.6h-1 were able to immediately utilize and grow with fructose, mannose, maltose and ribose. Galactose was transported instantaneously but growth star...

It has been recently suggested that there are likely generic features characterizing the emergence of systems constructed from the self-organization of self-replicating agents acting under one or more selection pressures. Therefore, structures and behaviors at one length scale may be used to infer analogous structures and behaviors at other length scales. Motivated by this suggestion, we seek t...

In an earlier paper @mouse, 1980), I described an extension of the classical mode1 of chemostat dynamics (Monod, 1949), which extension allows one to deal with competion for multiple limiting substrates. The object of the present paper is similarly to extend a simple chemostat mode1 of predation (Tsuchiya et al., 1972) to the case of multiple predators and multiple prey, both. underpinned by mu...

BACKGROUND One of the crucial factors for a sustainable and economical production of lignocellulosic based bioethanol is the availability of a robust fermenting microorganism with high tolerance to inhibitors generated during the pretreatment of lignocellulosic raw materials, since these inhibitors are known to severely hinder growth and fermentation. RESULTS A long-term adaptation in repetit...

In this paper, we consider a competition model between n species in a chemostat that incorporates both monotone and nonmonotone general response functions and distinct removal rates. We show that only the species with the lowest break-even concentration survives, provided that the variation of distinct removal rates relative to the flow rate of the chemostat can be controlled by either the diff...

A chemostat with two organisms competing for a single growthlimiting nutrient controlled by feedback-mediated dilution rate is analyzed. A specific feedback function is constructed which yields circular and elliptical periodic orbits for the limiting system. A theorem on the stabilization of periodic orbits in conservative systems is developed and for a given elliptical orbit, the result is use...

The production of lipids by oleaginous yeast and fungi becomes more important because these lipids can be used for biodiesel production. To understand the process of lipid production better, we developed a model for growth, lipid production and lipid turnover in submerged batch fermentation. This model describes three subsequent phases: exponential growth when both a C-source and an N-source ar...

By monitoring increases and decreases in the proportion of cycloheximide-resistant macroconidia, periodic selection was observed in populations of the filamentous fungus Fusarium graminearum, grown in glucose-limited chemostat cultures. The results indicated that periodic selection of advantageous mutants of F. graminearum occurred at intervals of about 124 h at both high (D = 0.19 h-1, approxi...

Long-term studies with a gliding, heterotrophic bacterium, Cytophaga johnsonae, were conducted in a glucose-limited chemostat at a high and a low dilution rate. To test the stability of the steady state during long-term experiments the following parameters were monitored: optical density, glucose concentration, glucose uptake potential, ATP content of the cells, and plate counts on two differen...