نتایج جستجو برای: chemoimmunotherapy

تعداد نتایج: 698  

Journal: :Blood 2009
Katherine I Lin Constantine S Tam Michael J Keating William G Wierda Susan O'Brien Susan Lerner Kevin R Coombes Ellen Schlette Alessandra Ferrajoli Lynn L Barron Thomas J Kipps Laura Rassenti Stefan Faderl Hagop Kantarjian Lynne V Abruzzo

Although immunoglobulin V(H) mutation status (IgV(H) MS) is prognostic in patients with chronic lymphocytic leukemia (CLL) who are treated with alkylating agents or single-agent fludarabine, its significance in the era of chemoimmunotherapy is not known. We determined the IgV(H) somatic mutation status (MS) in 177 patients enrolled in a phase 2 study of fludarabine, cyclophosphamide, and rituxi...

Journal: :Anticancer research 2004
Ira H Ames

Breast cancer is the most common form of noncutaneous malignancy in the United States. Since a plateau seems to have been reached in the efficacy of conventional therapy for this, as well as for other solid tumors, our laboratory has been studying the therapeutic potential of chemoimmunotherapy against the disease. Here we report on attempts to treat autochthonous mammary adenocarcinomas in C3H...

2014
Xin Chen Lalage M Wakefield Joost J Oppenheim

In a mouse model of breast carcinoma, the combination of cyclophosphamide and transforming growth factor β1,2,3 (TGFβ1,2,3)-targeting antibody achieved superior antineoplastic effects. This novel paradigm of synergistic chemoimmunotherapy promises to improve the clinical outcome of cancer patients with micrometastases, and thus deserves further investigation.

Journal: :Blood 2011
Gregory A Abel

In this issue of Blood, Danese and colleagues present a large database analysis of patterns of care and outcomes with respect to chemoimmunotherapy for older patients with chronic lymphocytic leukemia (CLL). Their analysis demonstrates some of the important benefits and limitations of health services research as it relates to hematology.

Journal: :Nihon Naika Gakkai Zasshi 1978

Journal: :Clinical Lymphoma Myeloma and Leukemia 2020

Journal: :The Cochrane database of systematic reviews 2007
A D Sasse E C Sasse L G O Clark L Ulloa O A C Clark

BACKGROUND Malignant melanoma, one of the most aggressive of all skin cancers, is increasing in incidence throughout the world. Surgery remains the cornerstone of curative treatment in earlier stages. Metastatic disease is incurable in most affected people, because melanoma does not respond to most systemic treatments. A number of novel approaches are under evaluation and have shown promising r...

Journal: :Cancer treatment reviews 1994
O Agboola

Specific interventions included in the review Various adjuvant treatments including chemotherapy, radiotherapy alone or in combination with chemotherapy, and chemoimmunotherapy. The drugs studied were: thiotepa, 5-fluorodeoxyuridine, mitomycin C, 5-fluorouracil, adriamycin, vincristine, cyclophosphamide, methyl CCNU, vinblastine, 1,3-bis(2 chlorethyl)-1-nitrosourea, tegafur, cytosine arabinosid...

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