Cancer is one of the most occurring diseases in developed and developing countries. Plant-based compounds are still researched for their anticancer activity and for their quantity in plants. Therefore, the modern chromatographic methods are applied to quantify them in plants, for example, UPLC-MS/MS (ultraperformance liquid chromatography tandem mass spectrometry). Therefore, the aim of the pre...

In this paper we show the seasonal and diurnal variation in the content of the four iridoids found in cultivars of Antirrhinum majus, antirrhinoside, antirrhide, 5-glucosyl-antirrhinoside and linarioside. The seasonal variation in total iridoid content showed a marked bimodal distribution with high total values (around 100mg/g dry matter) early and late in the season and a very low content of a...

The use of a radiosensitizing and anti-angiogenic agents might augment the efficiency of cancer radiotherapy. Therefore, the anti-angiogenic and radiosensitizing potency of Chelidonium majus (C. majus; CM) ethanolic extract was examined in the current study. Ehrlich ascites Carcinoma (EAC) cells were inoculated into mice to induce an experimental model of solid tumors. Mice with well developed ...

Consistent with our previous studies, we continue to evaluate the antioxidant potential of Greater celandine (Chelidonium majus L), a representative Papaveraceae family, collected from northern Poland using model muscle tissue rainbow trout (Oncorhynchus mykiss Walbaum). Therefore, in present study, oxidative stress biomarkers [2-thiobarbituric acid reactive substances (TBARS), protein modifica...

PURPOSE The aim of this study was to investigate in vitro cytotoxic activity of four methanolic crude plant extracts against panel cell lines. METHODS Methanolic extracts were tested for their possible antitumor activity and cytotoxicity using the 3-(4,5-dimetylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) assay on six cancer cell lines; non-Hodgkin's B-cell lymphoma (Raji), human leuk...