The cell-attached configuration of the patch-clamp technique was used to investigate the effects of taurine on the basolateral potassium channels of rabbit proximal convoluted tubule. In the absence of taurine, the previously reported ATP-blockable channel, KATP, was observed in 51% of patches. It is characterized by an inwardly rectifying current-voltage curve with an inward slope conductance ...

This paper focuses on a hydraulic radius separation approach used to calculate the boundary shear stress in terms of bed and wall shear stress proposed in a trapezoidal channel. The average bed and sidewall shear stress in smooth trapezoidal open channels are derived after using Guo & Julien (2005) early equations taking a part of an investigation to cover both rectangular and trapezoidal chann...

The present-day continental slope offshore Brunei Darussalam (NW Borneo) displays several networks of submarine channels possessing planform attributes similar to those observed in better studied river systems. We use shallow 3D seismic data to study one tributary network in detail. This network is located directly downslope from the shelf-edge Champion Delta and encompasses an area approximate...

_ ----------____-_.__________.__..____._... Introduction.-.._._..___.__.___...'_.._.._.___...___ Pleistocene and Recent deposits .......L.............. North Loup River valley near Elba._____._..___._ North Loup River valley near Burwell..__.__._.__ North Loup River valley downstream from Brewster. North Loup River valley upstream from Brewster... South Loup River valley near Cumro. ___________...

Water and debris fl ows exiting confi ned valleys have a tendency to deposit sediment on steep fans. On alluvial fans where water transport of gravel predominates, channel slopes tend to decrease downfan from ~0.10–0.04 to ~0.01 across wide ranges of climate and tectonism. Some have argued that this pattern refl ects grain-size fi ning downfan such that higher threshold slopes are required just...

Slope is one of a crucial terrain variables in spatial analysis and land use planning, especially in China Loess Plateau area where suffer from serious soil erosion disasters. DEM based slope extracting method has been widely accepted and applied in practice. However slope accuracy derived per this method usually does not match with their popularity. A quantitative simulation to slope data unce...

Fluvial drainage basin area is often related to channel length and local slope through power law relationships and the relatively small range of exponents observed in these relationships is thought to result from physical mechanisms. Proposed mechanisms assume that the observed correlation between drainage area and fluid discharge is caused by precipitation. Using high resolution DEMs of channe...

The state dependence of Na channel modification by the alkaloid neurotoxin veratridine was investigated with single-channel and whole-cell voltage-clamp recording in neuroblastoma cells. Several tests of whole-cell Na current behavior in the presence of veratridine supported the hypothesis that Na channels must be open in order to undergo modification by the neurotoxin. Modification was use dep...