The title compound, C(13)H(13)N(2)O(+)·Cl(-), (1), was obtained as a colorless crystalline by-product during the synthesis of N-(2-pyridylmeth-yl)benzoyl-amine (2). The C-O bond length of 1.231 (2) Å in the benzoyl unit of (1) is slightly elongated in comparison with isolated C=O double bonds as also observed for (2) [1.237 (2) Å]. The N-C bond length of 1.345 (2) Å in the benzoic acid amide un...

Antimicrobial susceptibility testing of Mycobacterium tuberculosis is essential for a successful treatment of patients, mainly those with a previous history of antituberculosis therapy. Susceptibility testing of strains requires their isolation from sputum samples within 24 to 48 h of collection and storage at 2° to 4°C. If the sample is left at room temperature or in refrigeration for longer p...

The title organic-inorganic salt, (C(7)H(11)N(2))(2)[LaCl(H(2)O)(8)]Cl(4)·3H(2)O, consists of two 4-(dimethyl-amino)-pyridinium and one [La(H(2)O)(8)Cl](2+) cations, four chloride anions and three solvent water mol-ecules. In the crystal, the various units are connected by N-H⋯Cl, O-H⋯Cl, O-H⋯O and N-H⋯O hydrogen bonds, forming a network of alternating organic and inorganic layers. The 4-(dimet...

Some N-alkyl pia-hydroxy styryl pyridinium halides, the alkyl moieties being methyl, hexyl and decyl, have been synthesised and the acid dissociation constants of these compounds in aqueous and surfactant solutions have been determined using spectrophotometric method . The alkyl chain does not have any substantial effect on the pKa values in aqueous and cationic surfactant (cetyl trimethylammon...

In defense of: • Glycerine (Page 4) • Cetyl Stearyl Alcohol (Page 5) • Animal Products (Beeswax, Lactic acid & Lanolin in one product each) (Page 5) • Para-aminobenzoic Acid (PABA) (Page 5) • Parabens (Page 6) o Hazardous and Useless Alternatives Exposed (Page 8) Silver Chloride (Page 8) Grapefruit Seed Extract [Adulterated with Benzethonium Chloride & Triclosan] (Page 8) In defense of: • Sodiu...

BACKGROUND & OBJECTIVES Sensitivity of Ziehl-Neelsen (ZN) method is known to be low for liquefied sputum smears. Information on the ZN sensitivity for centrifuged deposit smears is not known. This study was carried out to determine the sensitivity of ZN method for acid fast bacilli (AFB) in centrifuged deposit smears and liquefied sputum smears made from sputum samples transported in cetyl-pyri...

A new rotaxane containing the 3-amido-phenyl-triazolium group incorporated into the interlocked structure's axle component has been prepared by a chloride anion templated clipping strategy. Proton NMR titration experiments reveal that the interlocked host displays a high degree of halide anion recognition in competitive 1 : 1 CDCl3-CD3OD solvent mixture. Chloride and bromide anions are bound st...

Six synthetic antimicrobial steroids were examined for indications of their mechanism of action. Dequadin acetate, cetyl pyridinium chloride (CPC), and sodium deoxycholate were studied for comparison. Aerated cells of Sarcina lutea were washed, suspended in 1.06 M sucrose, and converted to protoplasts with 20 mug/ml of lysozyme. Lysis was measured optically at 650 mmu as a decrease in optical d...

Eye is a highly vascularised organ. There are chances that a foreign substance can enter the systemic circulation through the eye and cause oxidative stress and evoke immune response. Here the eyes of rabbits were exposed, for a period of 7 days, to 5 known ocular irritants: Cetyl pyridinium chloride (CPC), sodium salicylate (SS), imidazole (IMI), acetaminophen (ACT) and nicotinamide (NIC). The...