Cervical cancer is the that forms in tissue of cervix. It usually slow growing may not have symptoms but can be found with regular Pap tests and proper screening. Hence it absolutely necessary for health workers especially female to knowledge about cervical a positive attitude getting screening done as per Cancer Screening guidelines so early detection diagnosis leading decrease incidence disea...

ectopic thyroid tissue results from abnormal embryologic development and migration of the thyroid gland. true malignant transformation in ectopic thyroid tissue is extremely rare and is always diagnosed after surgical excision of the lesion by pathology examinations. there are well-documented cases of ectopic thyroid cancer while primary tumoral lesion occurs in the orthotopic thyroid, but only...

introduction : cervical screening has decreased the incidence and mortality of cervical cancer worldwide. due to a low incidence rate of cervical cancer in iran and several middle eastern countries, an opportunistic screening is available for women in this region. we aimed to design and validate a questionnaire about knowledge, attitude, and practice (kap) for cervical cancer and cervical scree...

The use of three dimensional in vitro systems in cancer research is a promising path for developing effective anticancer therapies. The aim of this study was to engineer a functional 3-Din vitro model of normal and cancerous cervical tissue.Normal epithelial and immortalized cervical epithelial carcinoma cell lines were used to construct 3-D artificial normal cervical and cervical cancerous tis...

The study aimed to investigate the state of human papillomavirus (HPV) infection in patients with cervical cancer in the Uyghur population in China and to identify miRNA as biomarker for cervical cancer and HPV infection. We also performed genotyping to determine the variation in the types of HPV. Using microRNA (miRNA) microarray technology, differential miRNA expression between HPV-infected c...

OBJECTIVE To study the methylation of the promoter of the p16 gene in cervical cancer patients and explore the correlation between methylation and the incidence of cervical cancer. PATIENTS AND METHODS We recruited 78 patients with cervical cancer and 48 healthy individuals. The methylation-specific PCR was used to detect the methylation status in the promoter of the p16 gene. The mRNA expres...

the purpose of this study was to describe the feasibility of a combined preoperative chemoradiation program ib-iia, bulky and suspicious iib by radical surgery in patients with stage ib-iib cervical cancer. from september 1999 to april 2002, 30 patients with carcinoma of the cervix were treated with preoperative external beam radiotherapy of 45 gy in 5 weeks. patients received concurrent contin...

tumor size seems to be a determinant in the prognosis of early cervical cancer. patients with tumor size greater than 4 cm (bulky) in diameter have worse outcome.' the purpose of this study was to compare the efficacy of preoperative combined chemoradiation and neoadjuvant chemotherapy (narc) programs followed by radical hysterectomy in stage ib - lib bulky cervical cancer. from september ...