Cancer of the uterine cervix (CC) is the second most common cancer in women worldwide. In Colombia, CC is the second most frequent cancer among the entire women population and the first among women aged between 15 and 44 years, with an estimated incidence of 24.9 cases/100,000 inhabitants. The main risk factor is infection with one or more high-risk human papillomavirus (HPV) types. The aim of ...

Persistent infection with high-risk HPV is the etiologic agent associated with the development of cervical cancer (CC) development. However, environmental, social, epidemiological, genetic, and host factors may have a joint influence on the risk of disease progression. Cervical lesions caused by HPV infection can be removed naturally by the host immune response and only a small percentage may p...

BACKGROUND This study presents the evaluation of the Mexico City Cervical Cancer Screening Programme (CCSP). Uterine cervical cancer (CC) is still a major public health problem in Mexico. Various actions aimed at reducing mortality from CC have been unsuccessful with an estimated 62000 deaths reported between 1980 and 1995. METHODS The authors performed a study of cases and controls chosen on...

BACKGROUND To investigate the infection status and predominant genotype distribution of human papillomavirus (HPV) infection among Chinese patients with mucopurulent cervicitis (MPC) or cervical cancer (CC) in Hangzhou. METHODS Initially, 217 cases of healthy cervix controls (n=50), acute MPC (n=89), and CC (n=78) were included; samples were collected between January 1, 2010, and January 30, ...

T his special issue of Salud Publica de Mexico presents an overview of the latest findings on prevention and screening of cervical cancer (CC), as well as new possible approaches to early diagnosis and intervention for controlling this neoplastic disease. Similar to other developing countries, CC persists in Mexico as a serious public health problem. Three main components to the burden of disea...

Cervical Cancer (CC) is a rapidly growing disease among women throughout the world, especially in developed and developing countries. For this many have died. Fortunately, it curable if can be diagnosed detected at an early stage taken proper treatment. But high cost, awareness, highly equipped diagnosis environment, availability of screening tests major barrier to participating or clinical tes...

Aberrant activation of the canonical Wnt pathway plays a significant role in cervical cancer (CC). However, limited data show the correlation between the cancer clinicopathological characteristics and the key molecules such as β-catenin and Wnt inhibitory factor 1 (WIF1). In this study, β-catenin and WIF1 expression were analyzed by immunohistochemistry for 196 patients with CC, 39 with cervica...

Cervical cancer (CC) is the second most common malignant cancer in women. CC is difficult to diagnose, has a high recurrence rate, and is resistant to systemic therapies; as a result, CC patients have a relatively poor prognosis. One potential link to CC is the Wnt signaling pathway and its downstream effectors, which regulate cell differentiation, proliferation, migration, and fate. The aberra...

Considering the crucial significance of the tumor microenvironment in cancer development and progression, the present study aimed to investigate the changes in macrophages and angiogenesis during the cervical cancer (CC) progression process from chronic cervicitis to cervical intraepithelial neoplasia grades I-III (CIN I-III) to CC. This investigation included quantitative analysis and assessme...

BACKGROUND Human papillomavirus (HPV) has proven to be the cause of several severe clinical conditions on the cervix, vulva, vagina, anus, oropharynx and penis. Several studies have assessed the costs of cervical lesions, cervical cancer (CC), and genital warts. However, few have been done in Africa and none in Swaziland. Cost analysis is critical in providing useful information for economic ev...