How head patterning is regulated in vertebrates yet to be understood. In this study, we show that frog embryos injected with Noggin at different blastula and gastrula stages had their development sequentially arrested positions. When timed BMP inhibition was applied BMP-overexpressing embryos, the expression of five genes: xcg-1 (a marker cement gland, which front-most structure embryo), six3 f...

The larval salivary gland of Drosophila melanogaster synthesizes and secretes glue glycoproteins that cement developing animals to a solid surface during metamorphosis. The steroid hormone 20-hydroxyecdysone (20E) is an essential signaling molecule that modulates most of the physiological functions of the larval gland. At the end of larval development, it is known that 20E--signaling through a ...

Five kinds of monoclonal antibodies that are specific for the epidermis of Xenopus embryos were produced. Epidermis-specific antibodies were used to investigate the spatial and temporal expressions of epidermal antigens during embryonic and larval development. The cells that were recognized by the antibodies at the larval stage are as follows: all of the outer epidermal cells and cement gland c...

Shaggy is a downstream component of the wingless and Notch signaling pathways which operate during Drosophila development. To address the role of glycogen synthase kinase 3 beta (GSK3 beta), a mammalian homologue of Shaggy, in vertebrate embryogenesis, it was overexpressed in Xenopus embryos. Microinjection of rat GSK3 beta mRNA into animal ventral blastomeres of 8-cell-stage embryos triggered ...

OBJECTIVE To compare biodegradable magnesium phosphate cement (Mg-cement), calcium phosphate cement (Ca-cement), and no cement on bone repair, biocompatibility, and bone adhesive characteristics in vivo in horses. ANIMALS 8 clinically normal adult horses. PROCEDURES Triangular fragments (1-cm-long arms) were created by Y-shaped osteotomy of the second and fourth metatarsal bones (MTII and M...

Solidia CementTM is a non-hydraulic cement composed primarily of low-lime containing calcium silicate phases such as wollastonite / pseudowollastonite (CaO·SiO2), and rankinite (3CaO·2SiO2). This contrasts the high-lime alite (3CaO·SiO2), belite (2CaO·SiO2), tricalcium aluminate (3CaO·Al2O3), tetracalcium aluminum ferrite (4CaO·Al2O3·Fe2O3), and gypsum (CaSO4·2H2O) phases that comprise ordinary...