Viruses are obligatory intracellular parasites that use cell proteins to take the control of the cell functions in order to accomplish their life cycle. Studying the viral-host interactions would increase our knowledge of the viral biology and mechanisms of pathogenesis. Studies on pathogenesis mechanisms of lyssaviruses, which are the causative agents of rabies, have revealed some important ho...

introduction the proteome is the full complement of proteins expressed by a cell or tissue at any given time or environmental condition. proteomics is the study and identification of this set or subset of proteins (abersold & man, 2003 cristea et al., 2004). whereas the genome is composed of all the potential genes that can be expressed as proteins, the proteome is composed of all proteins actu...

cell expansion and cell division are two main processes in plant growth and development. expansin proteins play a role key in cell expansion. these non-enzyme proteins involve in many growth and developmental processes. this protein affects drought tolerance. atexpb2 gene belongs to these proteins family. atexpb2 gene mainly expresses in the root tissue. in this study the expb2 gene, that was i...

background: the current study investigated the possible role of the cell cycle regulator, cyclin-dependent kinases regulatory subunit-2; the angiogenic factor, plateletderived endothelial cell growth factor; and the cell adhesive molecule, neural cadherin, as prognostic factors in schistosomal and non-schistosomal-associated urothelial carcinomas. we also investigated the possible correlation b...

Background: Basal Cell Carcinoma (BCC) is a type of non-melanoma skin cancer. Alteration in gene expression is the important event that happens in cancer cell. Detection of this event is possible by proteomics techniques. Methods: Normal and tumor tissues were taken from BCC patient. Total proteins were purified by standard methods, and proteins were separated by two-dimensional electrophoresis...

background: heat shock proteins (hsps) are a family of proteins that are known to play a significant role in the repair of denatured proteins in the cell. it seems that cytoprotective properties of hsps may help in malignant progression by facilitating tumor cell growth and survival. the purpose of this study is to evaluate hsp27 and hsp70 expression in various histopathological grades of squam...

Effects of excess concentrations of boron on major cell wall components of tobacco cells(Nicotiana tabacum L. cv. Burley 21) were studied. Pectin, xyloglucan, hydroxyproline-richglycoproteins (extensin), and arabinogalactan proteins were characterized. Results showedthat increased boron supply resulted in significant decrease in cell and cell wall dry weights.Also, high concentrations of boron ...

Objective(s): Crocin, as the main carotenoid of saffron, has shown anti-tumor activity both in vitro and in vivo. Crocin might interact with cellular proteins and modulate their functions, but the exact target of this carotenoid and the other compounds of the saffron have not been discovered yet. Microtubular proteins, as one of the most important proteins inside the cells, have several functio...