objective(s) the central nucleus of the amygdala (cea) is a forebrain structure which is important in regulation of ingestive behavior and there is direct and circumstantial evidence to indicate that some circuits involved with feeding behavior include glutamatergic elements. the present study examined whether administration of nma (n-methyl-dl-aspartic acid) or mk801 into the cea altered water...

objective: to evaluate the effect of dialysis and kidney transplantation on serum levels of several tumor markers such as psa, afp, ca125, ca19- 9, ca15-3, cea and to compare with normal age matched controls. methods: between september of 2000 and july of 2001, the following tumor markers: psa, afp, ca125, ca19-9, ca15-3 and cea were measured by elisa method in 29 hemodialyzed patients (group a...

Carcinoembryonic antigen (CEA), an oncofetal glycoprotein, is overexpressed in both colonic tumor tissue and in aberrant crypt foci. The 3' untranslated region (UTR) of CEA, which has been postulated to play a role in CEA expression, contains an oligo-A region. Sequence instability at oligo-A regions occurs in colorectal cancer, and it has been suggested that these mutations may alter expressio...

The tumours of 55 patients with colorectal carcinoma were evaluated for tissue carcinoembryonic antigen (CEA) by immunoperoxidase staining. It was shown that 33/35 patients with increased preoperative serum CEA levels above 5 ng/ml had positive tissue CEA. The other 17/20 patients who had serum CEA levels less than 5 ng/ml could be demonstrated CEA in tissue. The results of tissues CEA were com...

The carcinoembryonic antigen (CEA) domain specificities of a library of monoclonal anti-CEA antibodies were determined to investigate the mechanisms of homophilic binding involved in CEA-mediated intercellu lar adhesion. Using an indirect immunofluorescence cell surface staining technique, the reactivities of these antibodies were tested systematically on Chinese hamster ovary cells stably tran...

The binding reaction between carcinoembryonic antigen (CEA) and concanavalin A (Con A) has been studied. CEA, prepared from liver métastasesin patients with carcinoma of the colon, was tested against Con A for precipitation. By using the techniques of immunodiffusion and counlerelectrophoresis, a precipitate line between CEA and Con A was observed, which was different from that seen between ei...

The carcinoembryonic antigen (CEA) domain specificities of a library of monoclonal anti-CEA antibodies were determined to investigate the mechanisms of homophilic binding involved in CEA-mediated intercellular adhesion. Using an indirect immunofluorescence cell surface staining technique, the reactivities of these antibodies were tested systematically on Chinese hamster ovary cells stably trans...

OBJECTIVES Carcinoembryonic antigen (CEA) is widely used for postoperative surveillance of colon cancer. Even if serum CEA is negative at initial surgery, it may turn positive at recurrence. We investigated the relation between serum CEA levels and the immunohistochemical staining status of CEA in the primary and resected metastatic tissues. METHODS Out of 224 patients with recurrent colon ca...