The Differential Evolution (DE) population-based algorithm is an optimal algorithm with powerful global searching capability, but it is usually in low convergence speed and presents bad searching capability in the later evolution stage. A new Chaos Differential Evolution algorithm (CDE) based on the cat map is proposed which combines DE and chaotic searching algorithm. Firstly, the chaotic dist...

Regression aims at estimating the conditional mean of output given input. However, regression is not informative enough if the conditional density is multimodal, heteroskedastic, and asymmetric. In such a case, estimating the conditional density itself is preferable, but conditional density estimation (CDE) is challenging in high-dimensional space. A naive approach to coping with high dimension...

The choline-deficient, ethionine-supplemented (CDE) dietary model induces chronic liver damage, and stimulates liver progenitor cell (LPC) mediated repair. Long-term CDE administration leads to hepatocellular carcinoma in rodents and lineage tracing studies show LPCs differentiate into functional hepatocytes in this model. The CDE diet was first modified for mice by our laboratory by separately...

By R. R. RACE, M.R.C.S., L.R.C.P., A. E. MOURANT, B.M., B.Ch., MA., D. Phil., SYLVIA D. LAWLER, M.W, B.S., and RUTH SANGER, B.Sc.* T HIS paper reports the results of testing 1073 samples of blood, from English people, with the Rh antibodies anti-C, anti-C”, anti-c, anti-D, anti-E and anti-c. To these are added another 92.7, tested with anti-C, anti-c, anti-D and antiE, the results of which have...

Generative adversarial networks (GANs) have been a popular deep generative model for real-world applications. Despite many recent efforts on GANs that contributed, mode collapse and instability of are still open problems caused by their optimization difficulties. In this article, motivated the cooperative co-evolutionary algorithm, we propose dual evolution-based GAN (CDE-GAN) to circumvent the...

A new domino reaction for the highly selective synthesis of tetracyclic cinnolino[5,4,3-cde]cinnolines using steric control was described. In this reaction, the use of anthenes with aliphatic groups (R(1)) leads to cinnolino[5,4,3-cde]cinnolines whereas anthenes with aryl groups (R(1)) result in N-amino-1,8-dioxoacridines.

Virginia Valentine, CNS, BC-ADM, CDE; Karmeen Kulkarni, MS, RD, BC-ADM, CDE; and Debbie Hinnen, ARNP, BC-ADM, CDE The evolution of advanced practice in diabetes management has emulated the advanced practice efforts of nursing groups. However, many disciplines are involved in the care and education of people with diabetes. This article reviews the expanded role of health professionals in diabete...

ETHNOPHARMACOLOGICAL RELEVANCE In traditional Chinese medicines, Cortex Dictamni is prescribed for the treatment of a variety of inflammatory diseases such as acute rheumatoid arthritis, skin inflammation and jaundice. AIM OF THE STUDY This study was designed to investigate the effect of ethanol extract of Cortex Dictamni on treatment of hepatic fibrosis and its possible mechanisms. MATERIA...

NF-κB and its associated pathways are complicatedly concerned about hepatic homeostasis. Discriminating inhibition of NF-κB signaling has been expected to treat various liver diseases including fulminant hepatitis. To clarify the potential use of thioalkylated mannose-appended dendrimer (generation 3; G3) conjugates with α-cyclodextrin with average degree of substitution of mannose (DSM4) (Man-...

Bone marrow cells (BMCs) have been reported to behave as tissue-specific stem cells in some organs and to participate in tumorigenesis. However, the roles of BMCs in hepatic regeneration and carcinogenesis are still unknown. A choline-deficient, ethionine-supplemented (CDE) diet leads to the appearance of oval cells, a type of hepatic progenitor cell, and activates their replication. Furthermor...