BACKGROUND Celiac disease (CD) is an autoimmune disorder of the small intestine which is triggered by dietary gluten in genetically predisposed (HLA-DQ2/DQ8 positive) individuals. Only a fraction of HLA-DQ2/DQ8 positive individuals develop CD indicating that other factors have a role in the disorder. Several studies have addressed intestinal microbiota aberrancies in pediatric CD, but the resul...

Rats fed diets with cadmium (Cd) concentrations similar to that found in human diets, and nutritionally marginal with respect to iron (Fe), zinc (Zn), and calcium (Ca) retained 10 times more Cd in the duodenum than rats fed adequate mineral diets. In the current study, 2 experiments were performed to determine the role of intestinal metallothionein (MT) in the accumulation of duodenal Cd, and t...

Regulatory interleukin-10 (IL-10)-producing B cells (B10 cells) play a critical role in preventing and curing autoimmune diseases in experimental mouse models. However, the precise cellular and molecular mechanisms of action of B10 cells in humans, especially in patients with Crohn's disease (CD), remain to be determined. miR-155 regulates many physiological and pathological conditions, includi...

1.はじめに CGで現実感のある画像を生成する技術は、いかにして物体を 忠実に表現するかの技術である。物体を特徴付ける要素として は、大きく分けて、物体の形状と、物体表面の色情報や光学属 性などの表面属性がある。物体の表面属性を表現する場合、一 般的には、バンプマッピングなどのさまざまなマッピング手法 がとられている。CGデザイナがマッピングに利用できる素材と しては、市販の CD-ROM やインターネット経由で入手できる素 材集、およびテクスチャ生成のプログラムから出力されるデー タなどがある。 本報告で取り扱う石畳を表現する場合、CGデザイナが路面の 敷石を1つ1つモデリングして表現することが理想ではある が、大変な労力を要するため現実的ではない。一方、石畳の写 真素材を路面にマッピングして表現することも可能であるが、 以下のような問題が生ずる。 ・テクスチャ全体として凹凸が激し...

The hfarerirds Science Cimrion Index w on CD-ROM, a new specialty index launched by the Institute for Scientific Information’@, is discussed. The index contains searchable author abstracts,

measured HDRC Lars III C14 luminance output recovered resp. fitted resp. output recovered resp. fitted resp. recovered resp. [cd/m] 10 bit [cd/m] [cd/m] 16 bit [cd/m] [cd/m] [cd/m] 5.3 404 4.78 4.57 200 9.04 8.69 5.38 9.3 424 7.95 8.12 366 9.35 11.52 9.05 70.9 497 46.70 62.65 3,278 62.46 61.33 66.07 741.2 582 403.22 695.22 18,722 643.96 663.00 704.43 8,796 673 8,616.82 8,924.89 32,126 4,196.72 ...

Coeliac Disease (CD) is an immune-mediated systemic disorder elicited by the ingestion of gluten. Small-bowel biopsies and histology has been the gold standard for diagnosing CD. The modified ESPGHAN guidelines recommend that in symptomatic children with anti-tissue-Transglutaminase (tTG) titre of > 10 times Upper-Limit-of-Normal (ULN), diagnosis of CD can be made without small-bowel biopsies. ...

The inclusion of volatile derivatives of benzene and cyclohexane in β-cyclodextrin (β-CD), hydroxypropyl-β-CD, and hydrophilic β-CD-thioethers was investigated by static headspace gas chromatography (HS-GC) and molecular modelling. The obtained binding constants strongly increase with the amount of space filling of the CD cavity and the salt concentration. β-CD thioethers show a 3-10 times high...

OBJECTIVE Celiac disease (CD) is associated with type 1 diabetes (T1D). In the current study, we examined whether CD affects the risk of diabetic retinopathy (DRP) in patients with T1D. RESEARCH DESIGN AND METHODS This was a population-based cohort study. Through the Swedish National Patient Register, we identified 41,566 patients diagnosed with diabetes in 1964-2009 and who were ≤30 years of...

Food chain contamination by cadmium (Cd) is the most important pathway of Cd exposure to the general population, excluding smokers. Factors affecting transfer of Cd from soil and air to plants are reviewed. The direct deposition of airborne Cd in the plants has only a marginal influence on the crop Cd concentrations in rural areas with low atmospheric Cd deposition, i.e. < 2 g Cd ha(-1) y(-1). ...