نتایج جستجو برای: ccufe2o4sio2c3 pyrazole c4so3 h2pw
تعداد نتایج: 3198 فیلتر نتایج به سال:
The title compound, C(25)H(19)N(3), is composed of an aryl-substituted pyrazole ring connected to an aryl-substituted isoquinoline ring system with a dihedral angle of 52.7 (1)° between the pyrazole ring and the isoquinoline ring system. The dihedral angle between the pyrazole ring and the phenyl ring attached to it is 27.4 (1)° and the dihedral angle between the isoquinoline ring system and th...
Both the acetyl and phenyl substituents of the central pyrazole ring in the title compound, C(24)H(20)N(2)O(3)S, are twisted with respect to the pyrazole ring, with the twist involving the phenyl ring being greater [67.4 (1) and 29.6 (2)°]. The tolyl substituent is disordered over two positions in a 1:1 ratio; the mean planes of the aromatic ring are aligned at 67.7 (3) and 69.4 (3)° with respe...
Pyrazole is a five membered heterocyclic ring which is a versatile leading compound for designing potent bioactive agents. This interesting group of compounds has diverse biological activities such as antimicrobial, anti-inflammatory, analgesic, anticonvulsant, anticancer, anthelmintic, antioxidant and herbicidal. Results of numerous derivatives of different pyrazole and their substitutions are...
This work describes the rich self-assembly behavior obtained by grafting a pyrazole-derived platform at focal point of poly(benzyl ether) dendrons. Liquid crystals and supergels made out fibers are supramolecular organization non-discoid entities, they notably increment photoluminescence in these aggregated states (Aggregation-Induced Emission, AIE). The novel point, which is derived from 3,5-d...
Pyrazole ring containing heterocyclic molecules have been known to show biological activity. In this work, by realizing the cyclization reactions of diketonic Michael adducts, synthesis new pyrazole compounds was accomplished. Diketonic adducts were prepared in low-good yields addition acetylacetone nitrovinyl arene presence piperidine. obtained high via these molecules. Structures all and prod...
In search of new selective CB2 ligands, the synthesis and preliminary biological evaluation of novel 1,4-dihydroindeno[1,2-c]pyrazole hybrids of the highly potent prototypicals 5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)-N-fenchyl-1H-pyrazole-3-carboxamide 1 and 1-(2,4-dichlorophenyl)-6-methyl-N-(piperidin-1-yl)-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide 2 are detailed.We postulated that...
A series of 3,5-disubstituted pyrazole-1-carboxamides were obtained by treatment of chalcones with semicarbazide hydrochloride in dioxane containing sodium acetate/acetic acid as a buffer solution. N-acetyl derivatives of pyrazole-1-carboxamides were isolated in good yields either by treatment of the carboxamide derivatives with acetic anhydride or refluxing chalcones with semicarbazide in etha...
BACKGROUND The plant pathogenic fungus (such as Gibberella zeae, Fusarium oxysporum and Cytospora mandshurica) causes devastating disease in agriculture. The pathogenic fungus is responsible for billions of dollars in economic losses worldwide each year. In order to discover new fungicidal molecule with good fungicidal activity against G. zeae, F. oxysporum, and C. mandshurica, we sought to com...
The correlation between the in vivo toxicity and in vitro mutagenicity of dimethylnitrosamine and the activity of dimethylnitrosamine demethylase I (DMND I) after pyrazole treatment of rats was studied. The biological effects of pyrazole were measured either as toxicity to the rats or as mutations to Salmonella TA 92. A dose-response relationship was observed between DMND I activity and the adm...
Argininosuccinate synthase (ASS) is the rate-limiting enzyme in the urea cycle. Along with nitric oxide synthase (NOS)-2, ASS endows cells with the L-citrulline/nitric oxide (NO·) salvage pathway to continually supply L-arginine from L-citrulline for sustained NO· generation. Because of the relevant role of NOS in liver injury, we hypothesized that downregulation of ASS could decrease the avail...
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