The heterodimeric nuclear cap-binding complex (CBC) binds to the mono-methylated 5' cap of eukaryotic RNA polymerase II transcripts such as mRNA and U snRNA. The binding is important for nuclear maturation of mRNAs and possibly in the first round of translation and nonsense-mediated decay. It is also essential for nuclear export of U snRNAs in metazoans. We report characterization by fluorescen...

introduction: cone beam computed tomography (cbct) is a new method that is able to provide three-dimensional images in radiology and is useful for dentomaxillofacial imaging. this study aimed to investigate the cases administrated cbct by dentists of kerman (2015 year). methods: this cross-sectional study was conducted on dentists in kerman. the data were gathered using standard research questi...

The 7mG (7-methylguanosine cap) formed on mRNA is fundamental to eukaryotic gene expression. Protein complexes recruited to 7mG mediate key processing events throughout the lifetime of the transcript. One of the most important mediators of 7mG functions is CBC (cap-binding complex). CBC has a key role in several gene expression mechanisms, including transcription, splicing, transcript export an...

The Cipher Block Chaining (CBC) Message Authentication Code (MAC) is an authentication method which is widely used in practice. It is well known that the naive use of CBC MAC for variable length messages is not secure, and a few thumb rules for the correct use of CBC MAC are known by \folklore". The rst rigorous proof of the security of CBC MAC, when used on xed length messages, was given only ...

hnRNP F was identified in a screen for proteins that interact with human CBP80 and CBP20, the components of the nuclear cap-binding complex (CBC). In vitro interaction studies showed that hnRNP F can bind to both CBP20 and CBP80 individually. hnRNP F and CBC bind independently to RNA, but hnRNP F binds preferentially to CBC-RNA complexes rather than to naked RNA. The hnRNP H protein, which is 7...

Background: Perioperative blood loss is associated with total knee arthroplasty (TKA). The tranexamic acid (TXA) is a plasminogen activator inhibitor widely used to prevent bleeding. The Stryker CBC II ConstaVac Blood Conservation System (CBC II, Stryker) can avoid homologous blood. The purpose of this study is to compare the efficacy of intravenous and topical regimen of TXA in primary TKA, an...