Cholecystectomy is associated with increased risk in patients with liver cirrhosis. Moreover, cirrhosis and portal hypertension have been considered relative or absolute contraindication to laparoscopic cholecystectomy. As experience with laparoscopic cholecystectomy increased, we decided to treat cirrhotic patients via this approach. Between January 1994 and April 1995, nine patients with a Ch...

pulmonary aspergillosis is a well known entity occurring in immunocompetent persons. cutaneous aspergillosis, on the other hand, has been described in cases of suppressed immunity. recently, invasive aspergillosis has been reported in patients with subtle immune dysfunction such as those with critical illness and advanced cirrhosis. we report a case of scrotal aspergillosis in association with ...

In the vast majority of cases, ongoing hypoxemia in a cirrhotic patient is usually hepatopulmonary syndrome (HPS) until proven otherwise; in this case, HPS was suspected prior to any known diagnosis of cirrhosis. This is the first reported case in the literature whereby HPS and cirrhosis were diagnosed after the fact, rather than with the preexisting knowledge of liver cirrhosis.

INTRODUCTION Our aim was to develop consensus guidelines for use of recombinant activated factor VII (rFVIIa) in massive hemorrhage. METHODS A guidelines committee derived the recommendations using clinical trial and case series data identified through searches of available databases. Guidelines were graded on a scale of A-E according to the strength of evidence available. Consensus was sough...

the liver transplantation program was established at shiraz nemazee hospital in 1993. shortage of cadaver organ supply due to various social and legal issues urged us to develop a living-related liver transplantation (lrlt) program. so far 7 (6 males, 1 female) living-related liver transplantations have been performed at this center. the mean age of patients was 8.21 years (+/- 4.16), with a ra...

 Multiple genetic and environmental factors interact to determine an individual's predisposition to non-alcoholic fatty liver disease and its phenotypic characteristics. Association studies have found a number of alleles associated with the development of non-alcoholic steatohepatitis. Our aim was to investigate whether multiple risk-associated alleles may be present in affected monozygotic twi...

In a time-series, memory is a statistical feature that lasts for a period of time and distinguishes the time-series from a random, or memory-less, process. In the present study, the concept of "memory length" was used to define the time period, or scale over which rare events within a physiological time-series do not appear randomly. The method is based on inverse statistical analysis and provi...

The first patient presented with high grade fever, vomiting and right upper quadrant abdominal pain for 2 weeks. He had undergone drainage of splenic abscess elsewhere. Computed tomography revealed hypodense, cavitatory lesions with honeycomb pattern in liver and spleen suggestive of multiple abscesses (Figure 1). The liver abscess was drained. After an initial response to intravenous meropenem...

OBJECTIVE Refractory ascites is defined as a lack of response to high doses of diuretics or the development of diuretic related side effects, which compel the patient to discontinue the diuretic treatment. Current therapeutic strategies include repeated large-volume paracentesis and transjugular intrahepatic portosystemic shunts (TIPS). Peritoneovenous shunt (Denver shunt) should be considered ...