BACKGROUND AND PURPOSE Carotid fusiform aneurysms are most commonly treated with occlusion of the parent vessel. The purpose of our study was to assess the effectiveness of self-expanding, cobalt-alloy stents in the ablation of experimental fusiform aneurysms with preservation of the parent vessel in a carotid artery model. METHODS Porous metallic stents were placed endovascularly along the l...

introduction: arterial stiffness is an important predictor of cardiovascular risk. several indices have been  introduced to estimate the arterial stiffness based on the changes in the brachial blood pressure. since the  substitution  of  the  blood  pressure  changes  in  the  central  arteries  such  as  carotid  with  the  blood  pressure  changes in the brachial results in error in the blood...

Motivation Biomechanical modeling of atherosclerotic plaques is emerging as a useful tool to provide markers of plaque vulnerability. However, the success of this modeling effort depends on the accurate estimation of local mechanical properties along the diseased vessel wall. Recent studies in healthy carotid bifurcations reported differences in wall distensibility between common and internal c...

Patch angioplasty is the most common technique used for the performance of carotid endarterectomy. A large number of patching materials are available for use while new materials are being continuously developed. Surprisingly little is known about the mechanical properties of these materials and how these properties compare with those of the carotid artery wall. Mismatch of the mechanical proper...

Atherosclerosis is a lifelong process involving artery wall thickening. Increased wall thickness has been widely adopted as a preclinical surrogate marker of atherosclerosis. A prerequisite for such a surrogate marker is that it is a structural characteristic of the vessel wall that is not subject to acute changes. The purpose of this study was to examine the acute effects of vasodilator drug a...

A thorough understanding of the relationship between local hemodynamics and plaque progression has been hindered by an inability to prospectively monitor these factors in vivo in humans. In this study a novel approach for noninvasively reconstructing artery wall thickness and local hemodynamics at the human carotid bifurcation is presented. Three-dimensional (3D) models of the lumen and wall bo...

The effect of surface vibrations on the pressure-gradient-driven flows in channels has been studied. analysis considered monochromatic waves and laminar flows. effectiveness was gauged by determining pressure gradient correction required to maintain same flow rate as without vibrations. Waves propagating upstream always increase losses. Flow response downstream is more complex changes a functio...

Physical inactivity is a potent stimulus for vascular remodeling, leading to a marked decrease in conduit artery diameter. However, little is known about the impact of physical inactivity on artery wall thickness or wall:lumen ratio or the potential of exercise countermeasures to modify artery wall thickness. The purpose of the study was to examine the impact of 60 days of bed rest, with or wit...

Most Westem opera singers report feeling phonatory vibrations, i.e., vibrations caused by phonation, in different parts of their bodies while singing. As one perceives one's own voice quite differently from one's listeners, it has been hypothesized that phonatory vibrations may be useful as a feedback signal for the control of phonation. These vibrations have been examined in some articles whic...

BACKGROUND Although vascular damage in the noncoronary circulation is a major cause of complications in hypertension, relatively little is known of the in vivo geometry and function of the arterial circulation in patients with uncomplicated hypertension or of their relation to left ventricular hypertrophy, a marker of enhanced risk of cardiovascular complications. METHODS AND RESULTS Wall thi...