background common carotid artery (cca) ultrasound with measurement of intima-media thickness (imt) is a safe and noninvasive technique for assessing subclinical atherosclerosis and determining cardiovascular risks. moreover, the pattern of wall thickening in the brachial artery (ba) is rather diffuse compared to the carotid artery and may be a more sensitive indicator of long-term systemic expo...

Fluid mechanic forces play a key role in the early development and progression of cardiovascular diseases, which predominantly occurs in areas of disturbed flow and low wall shear stress (WSS). In the present study, we perform particle image velocimetry (PIV) measurements in an anatomically realistic transparent flow phantom of a human carotid artery. Steady blood flow conditions are simulated ...

Patch angioplasty is the most common technique used for the performance of carotid endarterectomy. A large number of patching materials are available for use while new materials are being continuously developed. Surprisingly little is known about the mechanical properties of these materials and how these properties compare with those of the carotid artery wall. Mismatch of the mechanical proper...

A thorough understanding of the relationship between local hemodynamics and plaque progression has been hindered by an inability to prospectively monitor these factors in vivo in humans. In this study a novel approach for noninvasively reconstructing artery wall thickness and local hemodynamics at the human carotid bifurcation is presented. Three-dimensional (3D) models of the lumen and wall bo...

BACKGROUND Atherosclerosis is a progressive disease that causes vascular remodeling that can be positive or negative. The evolution of arterial wall thickening and changes in lumen size under current "standard of care" in different arterial beds is unclear. The purpose of this study was to examine arterial remodeling and progression/regression of atherosclerosis in aorta and carotid arteries of...

BACKGROUND AND PURPOSE This article describes the prevalence of extracranial carotid atherosclerosis assessed by ultrasonography, its association with risk factors, and its relation to symptomatic coronary disease and stroke in men and women aged > or = 65 years. METHODS Maximum percent stenosis, maximum common carotid artery wall thickness, and maximum internal carotid artery wall thickness ...

A new method for segmentation of the carotid artery for classifying it as diseased or normal towards plaque diagnosis is proposed in this paper. Kernel Fuzzy CMeans clustering is used for segmenting the longitudinal section of the carotid artery using which the wall layers of the artery are identified for classifying it as diseased or normal. As a pre-processing step a–nonlinear mean filter is ...

Background and Purpose: This article describes the prevalence of extracranial carotid atherosclerosis assessed by ultrasonography, its association with risk factors, and its relation to symptomatic coronary disease and stroke in men and women aged >65 years. Methods: Maximum percent stenosis, maximum common carotid artery wall thickness, and maximum internal carotid artery wall thickness were a...

We have shown previously that TGA (transposition of great arteries) is associated with increased carotid artery stiffness. It has been established that stiffening of the barosensory vessel wall results in reduced baroreceptor activation and impaired BRS (baroreflex sensitivity). In the present study we tested the hypothesis that the increased carotid artery stiffness in TGA patients was associa...

BACKGROUND Arterial stiffness is an early marker of atherosclerosis. The carotid arteries are easily accessible by ultrasound and are commonly used for the evaluation of atherosclerosis development. However, this stiffness assessment is based on the elastic properties of the artery, which may be influenced by the adjacent internal jugular vein (IJV). The aim of the present study is to evaluate ...