نتایج جستجو برای: cargo separation
تعداد نتایج: 133984 فیلتر نتایج به سال:
Autophagy is a process delivering cytoplasmic components to lysosomes for degradation. Autophagy may, however, play a role in unconventional secretion of leaderless cytosolic proteins. How secretory autophagy diverges from degradative autophagy remains unclear. Here we show that in response to lysosomal damage, the prototypical cytosolic secretory autophagy cargo IL-1β is recognized by speciali...
Speed economy, proposed by Japanese scholars Masaki Tamura, refers to get the cost savings flow by accelerating the transaction process [1], which brings the a large market space to the cargo/express delivery industry [2]. Due to the rapidly growth of China air cargo/express market and the ongoing increasingly opening up of the sky, international cargo/express giants have set up their hubs in C...
An international study of the airport choice factors for non-integrated cargo airlines By John Gardiner Recent forecasts predict that the current number of all-cargo aircraft worldwide will more than double over the next 20 years, spurred on by trends such as reduced passenger belly hold capacity on short and medium haul routes and a growing recognition of the profit potential of cargo by airli...
This investigation has been carried out under a contract awarded by the Netherlands Directorate-General of Civil Aviation (RLD), contract number LI/99.121/2. Summary Previous research has suggested that cargo operators suffer a disproportionally high number of accidents. The degree of unsafety could however not properly be quantified due to lack of data. The objective of the underlying study wa...
Autophagy is a major pathway for the clearance of harmful material from the cytoplasm. During autophagy, cytoplasmic material is delivered into the lysosomal system by organelles called autophagosomes. Autophagosomes form in a de novo manner and, in the course of their formation, isolate cargo material from the rest of the cytoplasm. Cargo specificity is conferred by autophagic cargo receptors ...
Cargo is selectively exported from the ER in COPII vesicles. To analyze the role of COPII in selective transport from the ER, we have purified components of the mammalian COPII complex from rat liver cytosol and then analyzed their role in cargo selection and ER export. The purified mammalian Sec23-24 complex is composed of an 85-kD (Sec23) protein and a 120-kD (Sec24) protein. Although the Sec...
All newly made proteins destined to be secreted from our cells or to function at the cell surface—and many of those that function in membranes within the cell— start their lives in a convoluted heap of membranes within cells called the endoplasmic reticulum (ER). From there, they begin a journey that will take them through the stacked membrane compartments of the Golgi apparatus to their eventu...
چکیده ندارد.
Neurons secrete many diffusible signals from synaptic and other secretory vesicles. We characterized secretion of guidance cues, neuropeptides, neurotrophins, and proteases from single secretory vesicles using pHluorin-tagged cargo in cortical neurons. Stimulation triggered transient and persistent fusion events. Transient events represented full release followed by cargo diffusion or incomplet...
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