OBJECTIVES To determine the association between gastric intramucosal pH, a minimally invasive marker reflecting the adequacy of oxygen delivery to the gastrointestinal tract, and splanchnic endotoxin, antibody to endotoxin, and tumor necrosis factor (TNF)-alpha concentrations in patients undergoing cardiopulmonary bypass. DESIGN Single-arm, prospective study. SETTING University hospital. ...

The development and improvement of cardiopulmonary bypass technology is an ongoing process. During the past decade, a number of publications on improvements and best practices have appeared, especially in the areas of biocompatibility, materials sciences, instrumentation, monitoring of physiological parameters and knowledge base (education and evidence-based medicine). Biocompatibility may be d...

background: conduct of cardiopulmonary bypass (cpb) due to the higher volume of priming solution in comparison to the total blood volume in children requires careful consideration. recently attention has been focused on the potential risk of hyperkalemia in these patients. given its significant effects on cardiac rhythm, hyperkalemia is considered a medical emergency. in this cross-sectional st...

objective(s): to study the effect of cardiopulmonary bypass (cpb) on nuclear factor-kappa b (nf-кb) and cytokine expression and pulmonary function in dogs. materials and methods: twelve male mongrel dogs were divided into a methylprednisolone group (group m) and a control group (group c). all animals underwent aortic and right atrial catheterization under general anesthesia. changes in pulmonar...

conclusions: normothermia and hemodynamic stability are the most important factors which help to reduce fetal loss during open heart surgery in pregnancy. the fetus has an auto-regulation which comes into play when the mother is experiencing shock. objectives: the aim of this study was to report our experience with urgent cardiopulmonary bypass carried out in early pregnancy and to analyze fact...

OBJECTIVE To provide a brief review of the development of cardiopulmonary bypass. METHODS A review of the literature on the development of extracorporeal circulation techniques, their essential role in cardiovascular surgery, and the complications associated with their use, including hemolysis and inflammation. RESULTS The advancement of extracorporeal circulation techniques has played an e...

BACKGROUND Major surgeries such as open-heart surgery with cardiopulmonary bypass are associated with a complexity of stress response leading to post-operative complications. Studies have confirmed that anesthesia can mitigate the surgically induced stress response. OBJECTIVES The aim of this study was to compare the effects of propofol and isoflurane, both supplemented with Sufentanil, on th...

patients with coronary artery disease and left ventricular dysfunction have high mortality with non surgical (medical) treatment. coronary artery bypass grafting improves survival and the quality of life. recently, revascularization without cardiopulmonary bypass has been presented as a viable alternative. the aim of this study was to survey the result of coronary artery bypass grafting with of...