INTRODUCTION Computerized simulations of cardiac activity have significantly contributed to our understanding of cardiac electrophysiology, but techniques of simulations based on patient-acquired data remain in their infancy. We sought to integrate data acquired from human electrophysiological studies into patient-specific models, and validated this approach by testing whether electrophysiologi...

Optimal management of patients with implantable cardiac devices has become crucial, in the rapidly evolving field of cardiac electrophysiology. A clear understanding of device algorithms and growing programming options is essential to decipher many complex device behaviours. As any other areas in cardiac electrophysiology, working through unknown tracings as examples is the best way to familiar...

background: the advancement of technology in recent decades has been lead to use the electrophysiology cardiac devices. although these devices are used increasingly, but the frequency of subclinical infection is unknown. we investigate bacterial infections due to implantable cardioverter defibrillator (icds) in patients with endocarditis. m aterials and methods: population of the study was cons...

Lujan HL, DiCarlo SE. Cardiac electrophysiology and the susceptibility to sustained ventricular tachycardia in intact, conscious mice. Am J Physiol Heart Circ Physiol 306: H1213–H1221, 2014. First published February 21, 2014; doi:10.1152/ajpheart.00780.2013.—Cardiac electrophysiological dysfunction is a major cause of death in humans. Accordingly, electrophysiological testing is routinely perfo...

An investigation into the technical and commercial feasibility of computer-based interactive simulation of the human heart was conducted. An experimental research application was developed and served as a proof of concept for the simulation models during the research phase. The follow-on development phase will be directed towards a pre-production prototype of a virtual heart organ. The prototyp...

Mayo Clinic Electrophysiology Manual is a concise book on cardiac electrophysiology from the Mayo Clinic Scientific Press, published by the Oxford University Press. Preface from the Editor-in-Chief Prof. Samuel J Asirvatham ends with a very interesting note: “If there is one regret in choosing a career in cardiac electrophysiology, it is that I can never again experience the unparalleled wonder...

is now increasingly recognized by genetic screening. Association studies have identified numerous genes that are coupled to cardiac diseases, but the functional role of mutations in these genes is often not clear. The relations between the electrophysiological changes in patients with hereditary or chronic cardiac diseases is often far from clear. This calls for an integrated type of research, ...

2010 iii DEDICATION To Christina, whose love and support made this possible. iv EPIGRAPH In a few minutes a computer can make a mistake so great that it would have taken many men many months to equal it. –Anonymous With the GPU, this may be possible in just a few seconds. –Fred