Recently, Seddik Hammad from Heidelberg University published an interesting report about a frequent misinterpretation in research on liver fibrosis (Hammad et al., 2017): in mice repeated doses of carbontetrachloride (CCl4) cause a pattern of fibrosis, in which pseudolobules occur that are lined by fibrotic streets, which can be visualized by Sirius red staining. In the center of these pseudolo...

A new heterogeneous catalytic system, phase-boundary catalysis, for epoxidation of alkene with aqueous H2O2 is proposed. Amphiphilic titanium-loaded zeolite particles, a part of the external surface of which was covered with hydrophobic alkyl groups and the rest being left hydrophilic, were prepared by deposition of titanium species from titanium(IV) tetra-2-propoxide and attachment of octadecy...

Hepatoprotective activity of the ethyl acetate extract of Teucrium polium L. was investigated using rats with CCl4-induced liver damage. Specific biochemical parameters (glutathione peroxidase, superoxide dismutase, reduced glutathione and total antioxidative status) were estimated in blood and in liver homogenate. Lipid peroxidation in CCl4-intoxicated rats was evidenced by a marked increment ...

Adult hepatocytes and liver-cell progenitors play a role in restoring liver tissue after injury. For the study of progenitor cells in liver repair, experimental models included (a) surgical removal of liver tissue by partial hepatectomy; (b) acute injury by carbontetrachloride; (c) acute injury by d-galactosamine (GalN) and N-nitrosomorpholine (NNM); and (d) chemical hepatocarcinogenesis by fee...

Abstrak
 Kerusakan hati menjadi salah satu penyakit dengan prevalensi yang tinggi khususnya di negara berkembang. Penelitian ini bertujuan untuk melihat adanya efek ekstrak ethanol daun kelor (Moringa oleifera) terhadap proteksi fungsi dan histopatologi tikus putih (Rattus norvegicus) diinduksi karbontetraklorida (ccl4). serta menentukan dosis efektif dari kombinasi tersebut. dilakukan sec...

BACKGROUND The mechanisms of sepsis mortality remain undefined. While there is some evidence of organ damage, it is not clear whether this damage alone is sufficient to cause death. Therefore, we aimed to examine contribution of organ injury/dysfunction to early deaths in the mouse abdominal sepsis. METHODS Female OF-1 mice underwent either medium-severity cecal ligation and puncture (CLP-Onl...

BACKGROUND Anemia is a condition that has multiple origins. One such origin is the destruction of red blood cells' (RBCs) membrane induced by free radicals. Treatment of anemia could therefore be enhanced by the use of free radicals' scavengers potentially found in some medicinal plants. In this study, the protective effect of Harungana madagascariensis on the RBCs' membrane physiology was inve...

Sir: During a biosynthetic study of bleomycin (BLM), several peptides, structurally related to BLM, were isolated from the culture broth of Streplomyces verticillus. One of them, designated as P-3A, was crystallized from water (NAKATANI et al., unpublished) as an equimolar Cu(II)-complex. Acid hydrolysis of metal-free P-3A gave ~-aminoalanine (amine component V" of BLM), 2-(I-amino-2-carboxyeth...

This paper presents results of a comprehensive survey conducted to better understand concentrations and spatial variations of indoor and outdoor concentrations of volatile organic compounds (VOCs) in industrial, urban and suburban neighborhoods. Three cities, representing these types of neighborhoods in Michigan, USA were selected, and 30 to 50 homes were selected in each city. Duplicate or tri...