Bioconjugates represent a novel class of therapeutics that offer promise in the treatment cancer. These compounds are formed by combining targeting molecule, such as an antibody or peptide, with therapeutic agent, chemotherapy drug toxin. This approach allows for targeted delivery agent to cancer cells, minimizing damage healthy tissues and reducing side effects. have shown significant potentia...

background although medical oncologists can have an important role in controlling the cost of cancer treatment, there is little information about their attitudes toward the cost of cancer treatment and the impact of cost on their treatment recommendations, especially in low- and middle-income countries (lmics). in this study, we assessed the attitude of iranian medical oncologists toward some e...

Today, nanoscience has grown and developed in various medical and therapeutic areas, including cancer treatment. On the other hand, cancer and its types have been rumored and inclusive and many people suffer from this fatal and deadly disease. Currently, existing therapeutic method, including chemotherapy, radiotherapy, and etc., along with the therapeutic effect, cause complications that are u...

objective(s): irinotecan is a potent anti-cancer drug from camptothecin group which inhibits topoisomerase i. recently, biodegradable and biocompatible polymers such as poly lactide-co-glycolides (plga) have been considered for the preparation of nanoparticles (nps). materials and methods: in this study, irinotecan loaded plga nps were fabricated by an emulsification/solvent diffusion method to...

the application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. in recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. on the other hand, encapsulation of drugs into nanoparticles (nps) can improve...

Drug abuse is the use of drugs in amounts or by methods that harmful for health. disorders (DUD) are associated with a range adverse health outcomes including increased mortality rates [1, 2]. For example, patients opioid substitution treatment (OST) shown to have significantly higher non-drug-related Cancer than general population [3, 4]. According American Society, substance and addiction mak...

Artemisinin is used to treat multi-drug resistant strains of malaria and also in the early stages development as an anti-cancer drug.

Nowadays, Nano-sized drug delivery systems have been studied extensively for theirpotential in cancer therapy. Various drug nanocarriers are being developed including liposomes, micelles, and Virus like nanoparticles (VLNPs). VLNPs offer many advantages for developing smart drug delivery systems due to their precise and repeated structures and relatively large cargo capacities. Truncated ...

objective: the anti-cancer properties of curcumin, a poliphenol extract from the rhizome of curry, has been confirmed by many investigators. however, low levels of uptake, tissue distribution and rapid metabolism has limited its application as an anti-cancer drug. this study is aimed at increasing curcumin's water solubility due to a biodegradable, neutral and non-toxic micellar nano-carrier ca...