This paper describes a special purpose simulation tool, SCSIM, developed for analysing supply chain (SC) behaviour and performance in the presence of uncertainty. SCSIM treats a SC which includes a rawmaterial inventory, a number of in-process inventories, an end-product inventory and production facilities between them, linked in a series. Main sources of uncertainty inherent in the serial SC a...

Modern multi-core processors equipped with weak memory models like TSO exhibit executions which – due to store buffers – seemingly reorder program operations. Thus, they deviate from the commonly assumed sequential consistency (SC) semantics. Analysis techniques for concurrent programs consequently need to take reorderings into account. For TSO, this is often accomplished by explicitly modellin...

Because the insolubility of the scrapie prion protein (PrP(Sc)) has frustrated structural studies by x-ray crystallography or NMR spectroscopy, we used electron crystallography to characterize the structure of two infectious variants of the prion protein. Isomorphous two-dimensional crystals of the N-terminally truncated PrP(Sc) (PrP 27-30) and a miniprion (PrP(Sc)106) were identified by negati...

Based on experiments showing immunomodulatory effects of garlic (Allium sativum L.), we sought to see whether Allium hirtifolim Boiss., belonging to the same genus of garlic, has any effect on immune responses. Hydroalcoholic extract and polyphenolic fraction of A. hirtifolium bulbs were prepared. Allicin (diallyl thiosulfinate), a biologically active component, was identified in plant bulbs...

Based on experiments showing immunomodulatory effects of garlic (Allium sativum L.), we sought to see whether Allium hirtifolim Boiss., belonging to the same genus of garlic, has any effect on immune responses. Hydroalcoholic extract and polyphenolic fraction of A. hirtifolium bulbs were prepared. Allicin (diallyl thiosulfinate), a biologically active component, was identified in plant bulbs...

Unlike the supply chain (SC) design problemwhich deals with the configuration of a new SC, the redesign problem assumes that a SC already exists and focuses on its reconfiguration in order to take profit of the changing logistics, financial, and fiscal advantages offered by each country. First, this requires considering specific decisions and cost factors such as those associated with facility ...

Hardware vendors now provide heterogeneous platforms in commodity markets (e.g., integrated CPUs and GPUs), and are promising an integrated, shared memory address space for such platforms in future iterations. Because not all threads in a heterogeneous platform can communicate with the same latency, vendors are proposing synchronization mechanisms that allow threads to communicate with a subset...

The relationship between the structural connectivity (SC) and functional connectivity (FC) of neural systems is a central focus in brain network science. It is an open question, however, how strongly the SC-FC relationship depends on specific topological features of brain networks or the models used for describing excitable dynamics. Using a basic model of discrete excitable units that follow a...