نتایج جستجو برای: calcium channel blockers
تعداد نتایج: 379427 فیلتر نتایج به سال:
Calcium channel blockers are widely used antihypertensives. Mineralocorticoid receptor antagonists are also used to treat hypertension and heart failure. We report here that a number of widely used dihydropyridine class calcium channel blockers are able to inhibit aldosterone-induced activation of mineralocorticoid receptor. These dihydropyridines varied in the extent of their effect on mineral...
Background and Objective: Occurrence of atrioventricular block due to arterial blood pressure or left ventricular systolic dysfunction in patients treated with beta-blockers, calcium channel blockers or Digoxin has been investigated throughout a number of studies. As determination of block level is particularly important in determining how to treat patients, this study was launched to evaluate ...
Calcium channel blockers are important drugs for the treatment of chronic stable angina. However, negative inotropic and dromotropic effects may limit their usefulness in patients with atrioventricular conduction abnormalities or left ventricular dysfunction. A new generation of calcium channel blockers will soon be available that have a more vascular selective action than currently available a...
Objective(s) Calcium-channel blockers have an important role in the treatment of several cardiovascular disorders. Derivatives of 1, 4-dihydropyridine are one of the most potent calcium antagonists. In this study four novel ', 4-dihydropyridine calcium channel blockers were synthesized and their hypotensive properties were investigated in male rats. Materials and Methods Four 1, 4-dihydropyr...
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