In recent years, there have been published clinical reports dealing with cysts or tumors of the odontogenic character the extract of which revealed pathologic keratinizing or calcifying changes in the light of histopathologic examination Cl, 6, 8, 9, 10, 11, 12). These pathologic changes are said to give quite different histopathologic findings from those of the radicular cyst, follicular cyst ...

Calcifying epithelial odontogenic tumor is a benign neoplasm, but its local destructive potential may lead to the formation of major bone defects. Microscopically, there are some histological variants. Among them, we highlight the clear cell variant due to its more aggressive behavior and a higher incidence of relapse. In this context, it is pertinent to describe the clear cell variant of calci...

Background: Ameloblastin (AMBN) gene expresses an important protein that acts as a cell adhesion molecule. This protein plays an important role in maintaining the ameloblast secretory stage of differentiation by binding to them and inhibiting their proliferation. Due to the relationship of this protein in the differentiation and proliferation of odontogenic cells, here, we investigated this gen...

the calcifying odontogenic cyst (coc) is a rare odontogenic cyst. only 2% of all odontogenic cysts and tumors are coc. coc associated with odontoma (cocao) reported in 24% of cocs. cocao presents a greater incidence in female, with a ratio of 2 to 1. the highest incidence of cocao occurs during the second decade with a mean age of 16 years, most frequently occurring in the maxilla (61.5%). here...

The calcifying odontogenic cyst (COC) is a rare odontogenic cyst. Only 2% of all odontogenic cysts and tumors are COC. COC associated with odontoma (COCaO) reported in 24% of COCs. COCaO presents a greater incidence in female, with a ratio of 2 to 1. The highest incidence of COCaO occurs during the second decade with a mean age of 16 years, most frequently occurring in the maxilla (61.5%). Here...

the term calcifying odontogenic cyst (coc) was first introduced by gorlin in 1962. coc occurs mainly as an intra-osseous lesion in mandible or maxilla but the peripheral variation of coc has also been reported. the confusion about coc nature as cyst or tumor has not been resolved and a vast diversity has been shown in clinicopathologic aspects of coc. the purpose of this study was the review an...

SUMMARY Calcifying epithelial odontogenic tumors and calcifying odontogenic cysts are rare, benign odontogenic tumors. We report two cases of an exceptional combination of these tumors with either an ameloblastic fibroodontoma or an odontoma.

Calcifying epithelial odontogenic tumor (CEOT) is an uncommon odontogenic tumor with well-known histopathological features and a challenging treatment plan. Although some investigators advocate conservative approach as the treatment of choice, others believe in radical surgical excision to avoid recurrence or malignant transformation. The main objective of this case report is presenting an unus...

Calcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic neoplasm, locally aggressive, characterized by sheets and nests of polyhedral epithelial cells exhibiting eosinophilic cytoplasm or less often clear cytoplasm. Additional features include nuclear pleomorphism without mitotic activity, concentric calcifications, and deposits of amyloid. Herein, we present an additional e...