Vitamin D is produced endogenously when the skin is exposed to sunlight and can be obtained exogenously from a few natural food sources, from food fortification and from supplements. Generally, vitamin D intake is low < or = 2-3 microg/d in Europe. Casual exposure to sunlight is thought to provide most of the vitamin D requirement of the human population. However, skin synthesis of vitamin D ma...

OBJECTIVE Obtaining adequate vitamin D during pregnancy is important for the health of mother and child. Low circulating 25-hydroxyvitamin D (25OHD) concentrations, a measure of vitamin D status, have been reported in pregnant women in several countries; yet, there are few studies of pregnant Canadian women. We measured 25OHD concentrations in a multi-ethnic group of pregnant women living in Va...

Cryptomys hottentotus has no access to dietary or endogenous sources of cholecalciferol (D,). Serum concentrations of calcifediol (25(OH)D,) were undetectable ( < 5 ng/ml) and calcitriol (1,25(OH),D3), although detectable in plasma, was at a low concentration (31.40 (SEM 3.06 pglml). Despite their naturally impoverished vitamin D status, these animals exhibited highly efficient mineral absorpti...

INTRODUCTION Hypercalcemia is a known, but rare complication of histoplasmosis, a granulomatous disease. We present a case of chronic disseminated histoplasmosis, complicated by hypercalcemia, transiently worsening after initiation of antifungal treatment. CASE PRESENTATION A 61-year-old gentleman presented with shortness of breath, cough, weight loss, but no fever or hemoptysis. His physical...

BACKGROUND Considerable evidence suggests that oxidative stress affects diabetes mellitus (DM) and contributes to its complications. Vitamin D has been shown to possess antioxidant properties. The aim of this study was to determine the association between serum levels of calcifediol (25-OH-D), an indicator of vitamin D status, and lipid profiles with oxidative stress in patients with type 2 dia...

Several studies focused on the role of vitamin D (vitD) in pain chronification. This study vitD level and chronification extension headache disorders. Eighty patients with primary underwent neurological examination, laboratory exams, including serum calcifediol 25(OH)D, features assessment along three questionnaires investigating depression, anxiety, allodynia. The 86.8% population had migraine...

BACKGROUND   Depression in adolescence is common and early onset predicts worse outcome in adulthood. Studies in adults have suggested a link between higher total 25-hydroxyvitamin D [25(OH)D] concentrations and lower risk of depression. OBJECTIVES   To investigate (a) the association between serum 25(OH)D(2) and 25(OH)D(3) concentrations and depressive symptoms in children, and (b) whether t...

The Social Survey Division of the Office for National Statistics on behalf of the Department of Health carried out a survey between 1994 and 1996 of infant feeding practices of mothers of Bangladeshi, Indian, or Pakistani origin living in England. A blood sample was taken during October-November 1996 from a subsample of children aged 2 years for analysis of iron and 25-hydroxycholecalciferol (v...

The debate on the causal association between vitamin D status, measured as serum concentration of 25-hydroxyvitamin D (25[OH]D), and various health outcomes warrants investigation in large-scale health surveys. Measuring the 25(OH)D concentration for each participant is not always feasible, because of the logistics of blood collection and the costs of vitamin D testing. To address this problem,...