background: reduced bioavailability of nitric oxide (no) and the t?786c polymorphism of endothelial nitric oxide synthase (enos) gene have been reported as risk factors for the development of coronary artery disease (cad) with conflicting results. we investigated the association of plasma no levels, t?786c genetic polymorphism, and gene expression levels of enos with cad risk in an iranian subp...

Background: Traditional risk factors for coronary artery diseases are not very specific in identifying coronary artery disease (CAD). LDL cholesterol is a proven risk factor for developing coronary artery disease (CAD). However Indian populations with established CAD often have lipid levels within normal range. Oxidized LDL is seen as a sensitive marker for CAD, so it might be a better predicto...

Introduction: One of the strongest and most consistent predictors of morbidity and mortality of an individual is socio -economic status (SES) and coronary artery disease (CAD) is maybe the most prominent disturbance caused by socio-economic inequality. To investigate the relation between socio - economic factors with CAD this study was conducted in Yazd province. Materials and Methods:This retr...

  Background and Objectives: Cardiovascular disease is the most common cause of death in developed countries. In addition to traditional risk factors for cardiovascular disease, nowadays, accumulating evidence indicates that a variety of infections contribute to pathogenesis of atherosclerosis,  (We investigated whether Helicobacter pylori infection is related to Prevalence of coronar...

Although numerous cross-sectional studies have reported associations of hypertension, hypercholesterolemia, diabetes, smoking, and/or obesity with the presence of coronary artery disease (CAD), correlations of these risk factors for myocardial infarction (MI) with the degree or progression of CAD have been less consistent. Nevertheless, these risk factors are generally assumed to be major deter...

BackgroundCoronary artery disease (CAD) is the major cause of death in the world today. Many factors are responsible for causing CAD, but some patients have none of the known major risk factors, i.e. hypertension, diabetes, smoking, hyperlipidemia and family history of CAD. Recent studies suggest other factors such as lipoprotein a (LPa), fibrinogen and homocysteine as risk factors for CAD. The...

BACKGROUND Coronary artery disease (CAD) is the leading cause of mortality and morbidity in the United States (US), and South Asian immigrants (SAIs) have a higher risk of CAD compared to Caucasians. Traditional risk factors may not completely explain high risk, and some of the unknown risk factors need to be explored. This short review is mainly focused on the possible role of dysfunctional hi...

Diabetes mellitus is a major source of morbidity in developed countries and, among its comorbid conditions, atherosclerosis is perhaps the most important. Since the availability of insulin, up to three fourths of all deaths among diabetics can be directly attributed to coronary artery disease (CAD).1 In adult patients with diabetes, the risk of CAD is 3to 5-fold greater in than nondiabetics des...

OBJECTIVE To investigate the usefulness of N-terminal pro-brain natriuretic peptide (NT-proBNP) as a predictive marker for angiographically significant coronary artery disease (CAD) and CAD severity compared with other newer biochemical risk markers and classic risk factors in patients with clinically suspected CAD. DESIGN Cross-sectional evaluation of NT-proBNP in a large consecutive series ...

Increased plasma total homocysteine (tHcy) levels have been shown to be a risk factor for coronary artery disease (CAD). The common methylenetetrahydrofolate reductase C677T (MTHFR C677T) polymorphism has been reported to be a strong predictor of mild hyperhomocysteinaemia (HHcy). We assessed whether this mutation was associated with increased risk of CAD and plasma levels of tHcy. We also eval...