نتایج جستجو برای: caco 2 cell

تعداد نتایج: 3839619  

Journal: :Journal of virology 2004
Masaru Tamura Katsuro Natori Masahiko Kobayashi Tatsuo Miyamura Naokazu Takeda

Norovirus (NV), a member of the family Caliciviridae, is one of the important causative agents of acute gastroenteritis. In the present study, we found that virus-like particles (VLPs) derived from genogroup II (GII) NV were bound to cell surface heparan sulfate proteoglycan. Interestingly, the VLPs derived from GII were more than ten times likelier to bind to cells than were those derived from...

Journal: :Journal of controlled release : official journal of the Controlled Release Society 2002
Mohamed El-Sayed Mark Ginski Christopher Rhodes Hamidreza Ghandehari

The objective of this study was to investigate the influence of physiochemical parameters (such as size, molecular weight, molecular geometry, and number of surface amine groups) of poly (amidoamine) (PAMAM) dendrimers, on their permeability across Caco-2 cell monolayers. The permeability of a series of PAMAM dendrimers, generations 0-4 (G0-G4), was investigated across Caco-2 cell monolayers in...

Journal: :Microbiology and Immunology 2021

The aim of this study was to assess the modulatory effect TcpA in expression CEACAM1 adhesin molecule and IL-1, IL-8, TNF-α pro-inflammatory cytokines Coculture model Caco-2/PBMC (peripheral blood mononuclear cell) that can mimic intestinal milieu. gene from Vibrio cholerae ATCC14035 cloned pET-28a transformed into Escherichia coli Bl-21. recombinant TcpA-His6 protein expressed purified using N...

Journal: :American journal of physiology. Cell physiology 2000
Q Ding Q Wang Z Dong B M Evers

The specific mechanisms controlling intestinal cell differentiation remain largely undefined. The retinoblastoma (Rb) proteins (pRb, p130, and p107) appear crucial to the terminal differentiation process of certain cells through their association and repression of E2F transcription factors. We have examined the expression of pRb-related proteins p130 and p107 as well as the regulation of E2F du...

Journal: :The Journal of pharmacology and experimental therapeutics 2006
Naoki Kobayashi Atsutoshi Ikesue Sumit Majumdar Teruna J Siahaan

Transient modulation of E-cadherin-mediated cell-cell adhesion may improve paracellular drug delivery through biological barriers. Therefore, there is a need to develop an efficient method to evaluate cadherin peptides that can modulate the intercellular junctions. The objective of this study was to establish a novel assay to evaluate peptide activity in modulating E-cadherin-mediated homophili...

Journal: :jundishapur journal of microbiology 0
naheed mojgani biotechnology department, razi vaccine and serum research institute, karaj, ir iran; biotechnology department, national research institute of animal sciences, karaj, ir iran. tel/fax: +98-263457003845 fatimah hussaini research and development department, nature biotechnology company, karaj, ir iran narges vaseji biotechnology department, national research institute of animal sciences, karaj, ir iran

conclusions this research study proved the presence of viable probiotic lab microflora in the ewe milk with enhanced health benefits. the 2 selected lactobacillus strains could be exploited in dairy or pharmaceutical industry in future. objectives the probiotic efficacy of two lactobacillus strains namely lactobacillus pentosus lp05 and l. brevis lb32 was evaluated. they were previously isolate...

Journal: :Chemical and Pharmaceutical Bulletin 2004

Journal: :Molecular biology of the cell 2007
Annika M Sääf Jennifer M Halbleib Xin Chen Siu Tsan Yuen Suet Yi Leung W James Nelson Patrick O Brown

Posttranslational mechanisms are implicated in the development of epithelial cell polarity, but little is known about the patterns of gene expression and transcriptional regulation during this process. We characterized temporal patterns of gene expression during cell-cell adhesion-initiated polarization of cultured human Caco-2 cells, which develop structural and functional polarity resembling ...

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