FOR MORE THAN 3 DECADES, SINCE HIGH LEVELS OF HIGHdensity lipoprotein cholesterol (HDL-C) were first linked to a lower risk of developing cardiovascular disease, the notion of raising HDL-C levels has been regarded as a potentially ideal treatment to prevent cardiovascular disease. High-density lipoprotein cholesterol has generally been called the “good cholesterol” to distinguish it from low-d...

background: coronary artery disease (cad) is one of the leading causes of death and disability around the world. interaction between genetic and environmental factors determines susceptibility of an individual to develop coronary artery disease . lipoprotein lipase (lpl) play an important role in the metabolism of hdl-c ( high density lipoprotein cholesterol ), ldl-c (low density lipoprotein ch...

Purpose: The aim of this study is to analyze the utility lipid parameters individually and low-density lipoprotein cholesterol/high-density cholesterol (LDL-C/HDL-C) ratio as a possible risk marker for intracerebral hemorrhages (ICH).
 Materials Methods: This was multicenter, retrospective case-control that included 226 patients with ICH controls. Lipid were evaluated after 12 h fasting in...

Diabetes mellitus is associated with complications in several different systems of the body, and the incidence of diabetes is rapidly increasing worldwide. The objective of the present study was to evaluate the effect of aqueous extract of Cydonia oblonga Mill. Fruit on lipid profile and some biochemical parameters in streptozotocin-induced diabetic rats. The extract showed anti hyper lipidemic...

diabetes mellitus is a common endocrine disorder. anti-diabetic agents from natural and synthetic sources are available for the treatment of this disease. berberis integerrima is a medicinal shrub used in conventional therapy for a number of diseases. the aim of the present study was to investigate the effects of aqueous extract of berberis integerrima root (aebi) on some physiological paramete...

BACKGROUND High levels of the triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) ratio are associated with obesity, metabolic syndrome, and insulin resistance. OBJECTIVES We evaluated variability in the remaining lipid profile, especially remnant lipoprotein particle cholesterol (RLP-C) and its components (very low-density lipoprotein cholesterol subfraction 3 and intermediate-d...

Atherosclerosis, along with the resultant coronary artery disease (CAD), is a leading cause of mortality in industrialized countries. Significant attention has focused on the role of low-density lipoprotein (LDL) in the pathogenesis of CAD. A dyslipidemia characterized by a combination of abnormalities in the plasma levels of triglycerides and highdensity lipoprotein (HDL) cholesterol, with or ...

metabolic diseases in china have been on the rise in recent decades, partially due to reduced cereal consumption and excessive intake of low glycemic index (gi) foods such as meat and oil. although the relationship between dietary glycemic load (gl) and various metabolic diseases has been extensively studied worldwide, it is unclear whether dietary gl is related to blood lipid levels and dyslip...

OBJECTIVE Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis (RA). Systemic inflammation is proposed to play a fundamental role in the altered lipid metabolism associated with RA; however, the underlying mechanisms are unknown. We undertook this study to compare cholesterol and lipoprotein kinetics in patients with active RA with those in matched healthy volunteers. ...

Background: Reference measurements are used to screen for abnormal blood lipids. The problem is that these reference values obtained in one population cannot be effective for another population. This study aimed to determine the reference values for blood lipids profiles in the population aged 25-64 years in Yazd. Methods: This descriptive study was based on the data of  Yazd Health Study (YaHS...