نتایج جستجو برای: brucella abortus s99

تعداد نتایج: 6862  

2013
Marta A Almirón Mara S Roset Norberto Sanjuan

Brucella abortus causes brucellosis mainly in cattle. The infection is transmitted to humans by ingestion of animal products or direct contact with infected material. While the intracellular lifestyle of Brucella is well characterized, its extracellular survival is poorly understood. In nature, bacterial persistence is associated with biofilms, where aggregated cells are protected from adversit...

2017
Iman Hashemifar Faramarz Masjedian Jazi Abbas Yadegar Nour Amirmozafari

Background: Human brucellosis is a zoonotic disease caused by Brucella melitensis, Brucella abortus, and Brucella suis. Brucella causes a chronic disease, which subverts the immune defense system of their hosts. In this study, the prevalence of an important Brucella virulence determinant, prpA, which can modulate immune response, was determined in human isolates. Methods: Polymerase chain react...

Journal: :Journal of infection in developing countries 2015
Shahzad Ali Shamim Akhter Heinrich Neubauer Falk Melzer Iahtasham Khan Qurban Ali Muhammad Irfan

INTRODUCTION The objectives of the present study were to determine the seroprevalence and identify the causative agent of brucellosis in small ruminants in Pakistan. METHODOLOGY A total of 278 serum and 212 milk samples were collected from sheep and goats that had close contact with seropositive bovine herds. Data related to age, sex, location, and breed were collected on the sampling day. Se...

Journal: :Journal of infection in developing countries 2012
Martha Olivera Angel Paula Ristow Albert Icksang Ko Cecilia Di-Lorenzo

INTRODUCTION Brucellosis is a re-emerging zoonosis with new cases reported each year in many Latin American countries, but it is mostly under-recognized. This study presents a serological investigation of infection with Brucella abortus and Brucella canis in a poor urban community in the city of Salvador, Brazil. METHODOLOGY Human sera (n = 180) were randomly selected from 3,171 samples taken...

2012
Martha Olivera Angel Paula Ristow Albert I. Ko Cecilia Di-Lorenzo

Introduction: Brucellosis is a re-emerging zoonosis with new cases reported each year in many Latin American countries, but it is mostly under-recognized. This study presents a serological investigation of infection with Brucella abortus and Brucella canis in a poor urban community in the city of Salvador, Brazil. Methodology: Human sera (n = 180) were randomly selected from 3,171 samples taken...

Journal: :Zoonoses and public health 2017
A K M A Rahman C Saegerman D Berkvens F Melzer H Neubauer D Fretin E Abatih N Dhand M P Ward

To determine the role of different Brucella (B.) spp. in Bangladesh, 62 animal samples and 500 human sera were tested. Animal samples from cattle, goats and sheep (including milk, bull semen, vaginal swabs and placentas) were cultured for Brucella spp. Three test-positive human sera and all animal samples were screened by Brucella genus-specific real-time PCR (RT-PCR), and positive samples were...

بهمنی, نسرین, عربستانی, محمد رضا, علیخانی, محمد یوسف, غلامی, علی, هاشمی, حمید,

Background and purpose: Brucellosis is a zoonotic disease. Given that serologic test has some specific characteristics such as difficult growth, problems associated with culture, and cross-reactions with otherbacteria, in this study multiplex real-time polymerase chain reaction (PCR) method was used to detect the most common species of Brucella spp. Materials and methods: This experimental s...

2012
Jennifer A. Ritchie Adam Rupper James A. Cardelli Bryan H. Bellaire

Brucella spp. are highly adapted intracellular pathogens of mammals that cause chronic infections while surving and replicating in host monocytes and macrophages. Although monocytes are normally susceptible to infection, pretreatment with pro-inflammatory cytokine interferon-γ (IFN-γ) activates cellular defense mechanisms that increase intracellular killing of Brucella and prevents bacterial re...

Journal: :The Journal of biological chemistry 2013
Hye-Sook Kim Clayton C Caswell Robert Foreman R Martin Roop Sean Crosson

BACKGROUND Virulence of pathogenic bacteria is often determined by their ability to adapt to stress. RESULTS The Brucella abortus general stress response (GSR) system is required for chronic mammalian infection and is regulated by phosphorylation and proteolysis. CONCLUSION The B. abortus GSR signaling pathway has multiple layers of post-translational control and is a determinant of chronic...

2014
Hamed Alizadeh Mojtaba Salouti Reza Shapouri

BACKGROUND Brucellosis is an infectious disease that is caused by Brucella spp. As Brucella spp. are intramacrophage pathogens, the treatment of this infection is very difficult. On the other hand, due to the side effects of the brucellosis treatment regime, it is necessary to find new antimicrobial agents against it. OBJECTIVES The aim of this study was to investigate the antimicrobial effec...

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