SIMPLE, RAPID, AND EXTRACTIVE SPECTROPHOTOMETRIC METHODS WERE DEVELOPED FOR THE DETERMINATION OF SOME FLUOROQUINOLONES ANTIBIOTICS: gemifloxacin mesylate (GMF), moxifloxacin hydrochloride (MXF), and enrofloxacin (ENF) in pure forms and pharmaceutical formulations. These methods are based on the formation of ion-pair complexes between the basic drugs and acid dyes, namely, bromocresol green (BCG...

Four simple and sensitive extractive spectrophotometric methods have been described for the assay of Mirtazapine either in pure form or in pharmaceutical formulations. The developed methods involve formation of coloured chloroform extractable ion-pair complexes of the drug with bromocresol green (BCG), bromophenol blue (BPB), bromothymol blue (BTB) and bromocresol purple (BCP) in acidic medium....

The concentration of human serum albumin (HSA) indicates the health state of individuals and is routinely measured by UV spectroscopy with bromocresol. However, this method tends to overestimate HSA, and more critically, depends highly on the timing, in seconds, of the measurements. Here, we report an analog of 2',7'-dichlorofluorescein that can be used as a fluorescent sensor to quantify HSA i...

1. Two dyes, bromocresol purple and ethyl red, were tested for their ability to register solution and membrane changes resulting from the illumination of suspensions of isolated chloroplasts. 2. Bromocresol purple can measure the external (suspension) pH both rapidly and accurately if the following precautions are observed: (a) since bromocresol purple stimulates electron flow to oxygen, either...

Simple, rapid, and extractive spectrophotometric methods were developed for the determination of gatifloxacin (GT) in bulk and pharmaceutical dosage form. These methods are based on the formation of yellow ion-pair complexes between the basic nitrogen of the drug and three sulphonphthalein acid dyes, namely; bromocresol green (BCG), bromocresol purple (BCP), bromophenol blue (BPB) and bromothym...

Three sensitive, selective, rapid and easily reproducible spectrophotometric methods (A-C) have been developed for the determination of propranolol hydrochloride (PPH) as a hydrochloride free base propranolol (PPL) in bulk sample and in its dosage forms. These methods are based on ion-pair formation between propranolol as a hydrochloride and free base and three acidic (sulphonphthalein) dyes; n...