INTRODUCTION To examine the long-term efficacy and safety of duloxetine in the treatment of Japanese patients with diabetic neuropathic pain, we carried out a 52-week, randomized, open-label extension of a 12-week, double-blind, placebo-controlled study. MATERIALS AND METHODS Japanese adults with diabetic neuropathic pain who completed the double-blind study were eligible for this long-term s...

I analyze the genre preferences of UK film audiences, applying correspondence analysis to data produced for the BFI’s report Opening Our Eyes on the cultural contribution of film. Although there is a weak correlation between the interactively coded variable ‘gender-age’ and genre, I identify clear patterns of genre preferences that extend the original interpretation of this data showing how vie...

This was a 12-week, randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of duloxetine, a selective serotonin and norepinephrine reuptake inhibitor, in 354 female patients with primary fibromyalgia, with or without current major depressive disorder. Patients (90% Caucasian; mean age, 49.6 years; 26% with current major depressive disorder) received duloxetine 60 m...

OBJECTIVE To evaluate and compare the effects of transcutaneous electrical nerve stimulation (TENS) therapy on pain intensity and functional capacity in patients with either peripheral neuropathic pain or central neuropathic pain. METHODS A total of 40 patients (20 with peripheral neuropathic pain and 20 with central neuropathic pain) were included in this study. Pain severity, pain quality, ...

BACKGROUND The efficacy of local anesthetic wound infiltration for the treatment of acute and chronic postoperative pain is controversial and there are no detailed studies. The primary objective of this study was to evaluate the influence of ropivacaine wound infiltration on chronic pain after breast surgery. METHODS In this prospective, randomized, double-blind, parallel-group, placebo-contr...

The Brief Pain Inventory- Short Form (BPI-SF) and Revised Short-Form McGill Pain Questionnaire Version-2 (SFMPQ-2) are generic pain assessment tools used in research and practice for pain assessment in musculoskeletal(MSK) conditions. A comprehensive review that systematically analyses their measurement properties in MSKconditions has not been performed. This review protocol d...

BACKGROUND AND PURPOSE This was a prospective cohort study assessing data from 71 adult patients undergoing total knee arthroplasty (TKA) following a standardized fast-track program between January and July 2013. The objective was to examine the relationship between self-rated pain sensitivity, as measured by the Pain Sensitivity Questionnaire (PSQ), and postoperative pain after TKA. METHODS ...

BACKGROUND Opioid analgesics have proven efficacy in the short-term management of chronic cancer pain, but data on their long-term use is more limited. OROS(R) hydromorphone is a controlled-release formulation of oral hydromorphone that may be particularly well suited to long-term management of chronic cancer pain because it provides stable plasma concentrations and consistent analgesia with co...