objective(s):cytochrome p-450 1a1 is an important enzyme in the first phase of the metabolism of some carcinogens such as polycyclic aromatic hydrocarbons (pahs), as well as estrogen. the present study evaluates the existence of cyp1a1 polymorphism in a number of breast cancer samples. materials and methods: one hundred breast cancer patients and the same number of healthy controls were analyze...

background: we evaluated the efficacy of a simple belly-board device (bbd) designed and made in our department for reduction of small bowel inside the post-operative pelvic radiotherapy fields of rectal carcinomas. methods: a very simple bbd was designed and manufactured in our department. it was made of acrylic glass, and was 128 cm long, 40 cm wide, and 9 cm high, with a 25x25 cm square openi...

results based on the recent researches, certain mmps play critical role in breast cancer initiation, invasion, and metastasis. they can be regarded as predictive biomarkers of primary diagnosis and prognosis of breast cancer and have predictive value for evaluation of disease, tumor recurrence, invading of tumor cells to other sites and therapeutic outcomes. conclusions in summary, the results ...

background the incidence and mortality rates of breast cancer are high among filipino women. the lack of knowledge on preventive behavior and early detection related to breast cancer is considered a reason. conclusions women who were aware of risk factors for breast cancer possessed a higher education level and had knowledge of the association of risk factors with preventive behaviors and early...

breast metastasis of ovarian carcinoma is rare. to date, only 39 cases have been reported in the english-language  literature  so  far.  we  are  herewith  reporting  a  primary  ovarian  papillary  serous  cyst adenocarcinoma metastasing to breast and epsilateral supraclavicular node in a 58 year old female asthe first case in our centre, located at north-east india.  the purpose of reporting ...

background breast cancer is the most common malignancy in women around the world so finding new biomarkers for early detection and also study on molecular aspects of breast cancer is valuable. cancer testis genes are a group of genes expressed solely in testis and in a range of human malignancies. objectives in this study we determined the expression of cancer testis genes tsga10, tex101 and od...

background: breast cancer is the most common cancer and the leading cause of cancer death among the women worldwide. the risk of local and distant recurrence is the highest during the first two years following the initial treatment. very late relapse (after 12 years) is uncommon in breast cancer survivors. methods: herein, we report the characteristics and outcomes of 6 such cases of breast can...

objective: the objective of this study was to investigate inhibition and anti-cancer effects of linoleic acid on the mcf-7 and mda-mb-231 human breast cancer cells. materials and methods: cell lines human breast cancer mcf-7 (gdc055) and mda-mb-231 (htb-26) cell lines were obtained from atcc. mcf-7 estrogen receptor positive human breast cancer cell line and  the estrogen receptor negative huma...

background: th e second leading cause of cancer deaths in women is breast cancer. germline mutations in susceptibility breast cancer gene brca1 increase the lifetime risk of breast cancer. eighty-one large genomic rearrangements (lgrs) have been reported up to date in brca1 gene, and evaluation of these rearrangements helps with precise risk assessment in high-risk individuals. in this study, w...

background: the relationship between thyroid autoimmunity and breast cancer is a challenging subject. we aimed to investigate this association in women with breast cancer. methods: in this descriptive study, 41 women with newly diagnosed breast cancer before receiving any pharmacologic treatment and 38 healthy age-matched women were enrolled. anti tpo ab (anti-thyroid peroxidase antibodies), ft...