The main objective of this paper is to optimize biosurfactant production by Pseudomonas aeruginosa 2297 with statistical approaches. Biosurfactant production from P. aeruginosa 2297 was carried out with different carbon sources, and maximum yield was achieved with sawdust followed by groundnut husk and glycerol. The produced biosurfactant has showed active emulsification and surface-active prop...

This research aims to formulate and to optimize a nanoemulsion-based formulation containing fullerene, an antioxidant, stabilized by a low amount of mixed surfactants using high shear and the ultrasonic emulsification method for transdermal delivery. Process parameters optimization of fullerene nanoemulsions was done by employing response surface methodology, which involved statistical multivar...

In this work, Box-Behnken”s Response Surface Methodology (RSM) was applied to study the esterification reaction effectiveness of Ngbo pillarred activated clay catalyst. The monitored based on temperature, time duration, amount reactant, catalyst weight, and particle size. Box--Behnken’s indicates that clay-catalyzed reactions proceed through dual Acid-complex Alcohol-complex mechanisms, with Al...

Nisin is a bacteriocin approved in more than 50 countries as a safe natural food preservative. Response surface methodology (RSM) combined with artificial neural network-genetic algorithm (ANN-GA) was employed to optimize the fermentation medium for nisin production. Plackett-Burman design (PBD) was used for identifying the significant components in the fermentation medium. After that, the path...

The objective of the study was to optimize the nutrition sources in a culture medium for the production of xylanase from Penicillium sp.WX-Z1 using Plackett-Burman design and Box-Behnken design. The Plackett-Burman multifactorial design was first employed to screen the important nutrient sources in the medium for xylanase production by Penicillium sp.WX-Z1 and subsequent use of the response sur...

BACKGROUND In this research, the removal of natural organic matter from aqueous solutions using advanced oxidation processes (UV/H2O2) was evaluated. Therefore, the response surface methodology and Box-Behnken design matrix were employed to design the experiments and to determine the optimal conditions. The effects of various parameters such as initial concentration of H2O2 (100-180 mg/L), pH (...

A simple and sensitive method has been proposed for the amikacin sulphate determination. It is based on the inhibition of the chemiluminescence (CL) emission generated from the oxidation of luminol in alkaline medium by H2O2 catalyzed by Cu(II), due to the interaction caused by amikacin, which forms a robust complex with the catalyst. The optimization of the experimental and instrumental variab...