BHV-1 is an important pathogen of cattle. Because of its ability to induce immune suppression, BHV-1 is an important agent in the multifactorial disorder, bovine respiratory disease complex (BRDC). BHV-1 encodes several proteins that inhibit various arms of the immune system suggesting that these proteins are important in the development of BRDC.

Seven mouse hybridoma cell lines producing monoclonal antibodies (MAb) against an encephalitogenic strain of bovine herpesvirus type 1.3 (BHV-1.3) were established. The clones producing MAb were selected to be specific for BHV-1.3 by enzyme-linked immunosorbent assay. Only L1B neutralized virus without complement. With the addition of complement, five of the MAb neutralized BHV-1.3 but not the ...

Die vorliegende Arbeit wurde in kumulativer Form verfasst nach § 6 Abs. 2 der Development and validation of a triplex real-time PCR assay for the rapid detection and differentiation of wild-type and glycoprotein E-deleted vaccine strains of Bovine herpesvirus type 1. " Nur wer nicht sucht, ist vor Irrtum sicher. " (Albert Einstein)

a cross-sectional study with a random cluster sampling design was carried out to estimate the seroprevalence of bovine herpesvirus type 1 (bhv-1) in non-vaccinated dairy herds in hamedan province, west of iran. simple random sampling was used for selection of cattle in each herd. informative data about each herd and selected animals were recorded by the farm manager in a provided questionnaire....

Treatment of bovine alveolar macrophages (BAM) with bovine leukocyte interferon (BoIFN-alpha 1) resulted in reduced bovine herpesvirus type 1 replication and spread. This was demonstrated by reduced virus yields and number of cells infected. BoIFN-alpha 1 treatment of BAM also induced enhanced Fc receptor expression and/or avidity by the cells, increased their activity in antibody-dependent cel...

Aim: To characterize one of the major glycoprotein genes viz., glycoprotein C (gC; UL44, unique long region 44) of bovine herpesvirus 1(BoHV1) of Indian origin at genetic and phylogenetic level. Materials and Methods: A bovine herpesvirus 1 isolate viz., (BoHV1/IBR 216 II/ 1976/ India) maintained at Division of Virology, IVRI, Mukteswar was used for the current study. The DNA was extracted usin...