A male fetus of gestation day 187 was aborted from a Holstein-Friesian cow in an epizootic of the Aino virus (AINOV) in September 1995. Neutralizing antibody titers against AINOV were 1:128, 1:16 and 1:64 in the dam serum, fetal ascites and cerebrospinal fluid, respectively. A 10% brain suspension of the aborted fetus was prepared immediately after autopsy, rinsed three times and sonicated befo...

Bovine genital campylobacteriosis (BGC) is a true venereal disease of cattle. This disease results in infertility, embryonic and fetal death, metritis, salpingitis, pyometra, and abortion in cattle, and sheep and goats as well. The causal agent of BGC, is Campylobacter fetus. This organism is found worldwide and causes significant economic losses in endemic areas where appropriate management ha...

In vitro transformation of brain cells of hamsters at various ages was examined after the addition of bovine adenovirus type 3 to determine the type and origin of the target cells. Cellular transformations occurred only in cultures of fetus and newborn animals and at low incidences. Nine cell lines were obtained. Virus specific tumor antigens were demonstrated in the transformed cells. The pres...

Infectious reproductive diseases have great potential to create significant damaging effects to reproductive efficiency and therefore profitability for the beef herd. Pathogens causing reproductive diseases include: bovine viral diarrhea (BVD), infectious bovine rhinotracheitis (IBR), Leptospira, Tritrichomonas foetus, Campylobacter fetus subsp. venerealis (“vibrio”) and Neospora caninum, among...

The isolation in pure culture of a definite morphological entity (vibrio or spirillum) with practically the same biological characters from a series of cases of the same clinical complex (abortion) establishes a presumption in favor of the specific identity of the organisms and also in favor of the inference that such organisms are etiologically related to the diseased condition. This presumpti...

Pregnancy involves volume overload, cardiac enlargement, and heart valve remodeling. The mitral remodels via increased leaflet area, composition, mechanics—and remarkably an increase in the number of chordae attachments. This is striking contrast to pathological remodeling as failure. Indeed, we hypothesize that maternal during pregnancy recapitulates fetal developmental mechanisms. To test thi...