The aim of this study was to evaluate and compare the effectiveness three different intra-articular injective treatments: hyaluronic acid (HA), autologous conditioned serum (ACS) bone marrow aspirate concentrate (BMAC) for treatment knee osteoarthritis (OA). A Level III retrospective comparative clinical performed on 505 consecutive patients treated with HA (n = 171), ACS 222) or BMAC 112) OA. ...

Objectives: A randomized control trial demonstrated evidence of earlier graft remodeling and improved 9-month International Knee Documentation Committee (IKDC) scores when anterior cruciate ligament reconstruction (ACLR) with bone-tendon-bone allograft was augmented an intra-graft injection bone marrow aspirate concentrate (BMAC). While these results are promising, the mechanism by which BMAC m...

IntroductionTreatment of infected non-unions the tibia is a challenging problem. The cornerstones optimal non-union treatment consist extensive debridement, fracture fixation, antimicrobial therapy and creation an local biological bone healing environment. combination S53P4 bioactive glass (BAG), as osteostimulative antibacterial graft substitute, marrow aspirate concentrate (BMAC) for implanta...

The aim of the study was a comparative evaluation bone marrow aspirate concentrate (BMAC) and platelet-rich plasma (PRP), administered intraosseously to patients with stage IIIII knee osteoarthritis (OA) according Kellgren Lawrence (K-L) classification. Materials methods: 40 were recruited divided into 2 groups for multicenter randomized study. Patients in main group (n = 19) underwent single i...

Refractory wounds in diabetic patients present a significant clinical problem. Sonic hedgehog (SHH), a morphogenic protein central to wound repair, is deficient in diabetes. Regulation of SHH in wound healing is poorly understood. We hypothesize that thrombospondin-1 (TSP-1), through its receptor CD36, contributes to the SHH signaling defect in bone marrow-derived angiogenic cells (BMACs) in ty...

We present two MAC layers for ultra-low-power wireless networking, BoX-MAC-1 and BoX-MAC-2. Leading lowpower MACs today reside in a single layer: BMAC exploits only the physical-layer while XMAC utilizes only the link-layer. In contrast, BoX-MAC-1 and BoX-MAC-2 are cross-layer protocols. BoX-MAC-1 incorporates link-layer information into a predominantly physical-layer sampling approach. BoX-MAC...

BACKGROUND Oxidative stress has been implicated in the major complications of diabetes mellitus, including retinopathy, nephropathy, neuropathy and accelerated coronary artery disease. There is a clinical need for a marker of oxidative stress which could potentially identify diabetic patients at increased risk for these complications. We measured oxidative age, a new breath marker of oxidative ...

The adhesion of bacterial pathogens to host cells is an event that determines infection, and ultimately invasion and intracellular multiplication. Several evidences have recently shown that this rule is also truth for the intracellular pathogen Brucella. Brucella suis displays the unipolar BmaC and BtaE adhesins, which belong to the monomeric and trimeric autotransporter (TA) families, respecti...