HARLAN, JAMES C., ELVIN E. SMITH, AND T. Q. RICHARDSON. Pressure-volume curves of the systemic and pulmonary circuit. Am. J. Phvsiol. 213(6): 1499-1503. 1967.-Mean svstemic pressure (klSP) and mean pulmonary pressure (MPP) were measured in eight mongrel dogs immediately after acute changes in blood volume. A decrease in blood volume of only 12 % decreased MPP to 0 mm Hg and decreased MSP to onl...

Despite growing concerns over mercury (Hg) exposure to humans and wildlife on a global scale, little is known about Hg bioaccumulation in the New World tropics. From 2005 to 2011, we monitored Hg concentrations in blood of nine avian species occupying a geographic range of tropical wet broadleaf sites on the island of Hispaniola, including eight passerines (two Nearctic-Neotropical migrant and ...

BACKGROUND Mercury (Hg) is toxic to both the reproductive and nervous systems. In addition, glutathione S-transferases (GSTs), which conjugate glutathione to a variety of electrophilic compounds, are involved in the detoxification of Hg. OBJECTIVE In this study we examined the association between prenatal exposure to Hg and birth weight as well as the influence of GST polymorphisms. METHODS...

OBJECTIVES To assess the efficacy of a public health intervention to reduce blood mercury (Hg) concentration levels in pregnant Bermudian women. METHODS In 2003, we conducted a study entitled "Prenatal exposure of the Bermudian Population to Environmental Contaminants" which provided Bermuda's first baseline data on prenatal exposure to several environmental contaminants, including Hg. The me...

Previous studies have reported results on 24-hour ambulatory blood pressure (ABP) in Europe and Japan, but no data exists from South America. In this study, we conducted a population survey to identify reference values and to compare ambulatory blood pressure with clinic, home, and self-measured values. A random sample of 2650 adults was selected among 190 000 people covered by our prepaid heal...

The relation between parental history of hypertension and blood pressure response to potassium intake is unknown. A 7-day high-sodium followed by a 7-day high-sodium plus potassium dietary-feeding study was conducted from 2003 to 2005 among 1,871 Chinese participants. Those with a maternal history of hypertension had larger systolic blood pressure responses to potassium compared with those with...

Previous studies have reported results on 24-hour ambulatory blood pressure (ABP) in Europe and Japan, but no data exists from South America. In this study, we conducted a population survey to identify reference values and to compare ambulatory blood pressure with clinic, home, and self-measured values. A random sample of 2650 adults was selected among 190 000 people covered by our prepaid heal...

BACKGROUND Masked hypertension (MH) is defined as a normal blood pressure in the physician's office and an elevated blood pressure when measured out-of-office. The cause of MH may be termed the masked hypertension effect (MHE), and is not restricted to blood-pressure (BP) values around the thresholds for normal BP. We investigated the prevalence and persistence of MH and MHE in patients who wer...

Mercury (Hg) is a widespread neurotoxic compound that bio-accumulates in fish and marine mammals. Monoamine oxidase (MAO; EC 1.4.3.4) regulates biogenic amine concentration in the brain and peripheral tissue and has been shown to be a molecular target of Hg compounds in animal models. Blood platelet monoamine oxidase-B (MAO-B) activity may reflect MAO function in the central nervous tissue. The...

The deleterious effects of mercury (Hg) contamination are well documented in humans and wildlife. Chronic exposure via diet maternal transfer two pathways which increase the toxicological risk for wild populations. However, few studies examined physiological impact Hg crocodilians. We investigated neonate Smooth-fronted Caimans, Paleosuchus trigonatus , use keratinized tissues blood to evaluate...