Blood platelets contribute to normal haemostasis in two main ways. They adhere to subendothelial microfibrils and collagen in the blood vessel wall, after which they change shape, undergo a specific release reaction, and aggregate with each other to form a primary haemostatic plug. As a consequence of these events, particularly during release and aggregation, procoagulant activities are generat...

Introduction: Kidney dysfunction, coagulopathy disorders, and lung involvement are the most common disorders caused by COVID-19 virus. Objectives: This study aimed to investigate correlation of severity with kidney dysfunction in patients. Patients Methods: descriptive-analytical was conducted on 97 patients referred Imam Reza hospital Kermanshah from December 2020 June 2021. Lung severity, fun...

Congenital bleeding disorders account for approximately one in 10,000 births. Dentists are often anxious about delivering treatment to this special group of patients. In the Irish Republic, patients with inherited bleeding disorders have their dental care co-ordinated centrally at the National Centre for Hereditary Coagulation Disorders (NCHCD), St James's Hospital, Dublin. Dental care is norma...

www.aafp.org/afp AMERICAN FAMILY PHYSICIAN 419 vessel wall and, in response to the exposed subendothelial collagen, release adenosine diphosphate (ADP) and thromboxane A2. The released ADP and thromboxane A2 cause further platelet aggregation and the formation of a platelet plug that is responsible for primary hemostasis. Secondary hemostatic mechanisms consist of a series of sequential enzymat...

The risk of severe haemorrhage in pregnancy is well recognized, and uncontrolled bleeding remains a major cause of maternal death throughout the world, including the British Isles. The haemochorial system of human placentation carries with it an inherent risk of haemorrhage and this probably explains why the serious congenital disorders of haemostasis are predominantly found in the male. In pre...

The novel coronavirus (SARS‑CoV‑2) infection manifested by a pandemic and has wide range of complications, including the nervous system’s complications. Despite fact that older people with comorbidities are more at risk developing complications from sequelae previous COVID‑19 disease, significant link between cerebrovascular disorders in young middle‑aged is increasingly mentioned literature. de...

It is usual to think of nonlinear dynamics while modeling problems with the heart [8] and the brain [7] cells. Some known hematological disorders that are of dynamical nature are centered around blood cells [14]. In this letter, we try to bring to light many more dynamical problems with blood coagulation that are centered around proteins and, in particular, an usual suspect named thrombin. We d...