background: vast variety of intermediate factors including cell cycle regulators, growth factors, transcription factors, and signaling pathways are involved in hematopoietic stem cell (hsc) commitment and differentiation into distinct lineages. vhl, ecad, and runx3 are among these. epigenetics is currently introduced as a potential mechanism to control the gene regulation. the aim of this study...

background & objective: there are many common infections and inflammations among people over the world. this demands an affordable and reliable test with high sensitivity/specificity to predict or confirm the diagnosis of such cases in routinely clinical practice. in the present study, we aimed to find any potential correlation between serum levels of ggt and crp- q and/or hs- crp and wbc c...

Background: Umbilical cord blood (UCB) is an alternative source of hematopoietic stem cell transplantation (HSCT), used in Leukemia treatment. CD26+ cells, a fraction of CD34 positive cells, are a major population of UCB cells which negatively regulate the in vivo homing and engraftment of HSCs. CD26 is highly expressed in various cells such as HSCs, immune cells, fibroblasts, and epithelial ce...

in this center, from 1991 to 2002, 89 chronic myelogenous leukemic (cml) patients, age ranging between 8-48 years with a median age of 29, underwent hematopoietic stem cell transplantation. eighty-eight patients were in the first chronic phase of disease. twenty-three patients received bone marrow transplantation (bmt) and 66 patients received peripheral blood stem cell transplantations (pbsct)...

background : this study was designed to investigate whether there was an association between abo blood groups and car­diovascular risk factors in healthy population. methods : in this cross-sectional study, risk factors screening for cardiovascular disease(cvd) on 5000 healthy persons of go­lestan province, northern iran, in 2005 was estimated by a questionnaire that included age, sex, physical...

background : hypertension is a risk factor for life threatening diseases such as cerebrovascular accidents, coronary artery diseases, congestive heart failure and chronic renal failure. the prevalence of non-communicable diseases such as hypertension and diabetes including obesity has increased over the past few years in iran. the first step for modification of cardiovascular diseases in a defi...

mankind efforts for achieving a better life while brings welfare for him, unfortunately brings environmental and harmful effects on health. these harm specially the ones due to increase in automobiles and fossil fuels, endanger the possibility of the continuation of life for present and future tenerations. lead is mentioned as one of the outputs of these fuels. available studies indicate that t...