Background: Acetaminophen (N-Acetyl-p aminophenol; APAP) is one of the most common types of analgesics. It is also the most common xneobitic reported to poison centers. This study investigates if therapeutic doses of NAC can falsely increase coagulation tests, prothrombin time (PT) and bleeding time (BT). ​​ Methods: Thirty-six APAP poisoned patients whose acetaminophen serum concentration were...

conclusions the high prevalence of vwd among our patients was the same as other previous reports, suggesting low awareness about this disease and under diagnosis of mild cases. results mean age of our patients was 32.5 ± 10.6 years. the level of von willebrand factor in 22.5% and von willebrand activity in 19.6% of patients was abnormal. the prevalence of vwd among patients with menorrhagia was...

Dear Editor, I read with interest the article by Yazdani, M, et al, on the administration of magnesium sulfate to women with premature labor and its effect on the bleeding time, published in the Iranian Journal of Medical Sciences.1I found it interesting but I would like to make some points regarding to this study:There are several methods for the measurement of bleeding time (BT). Those includ...

conclusions our study showed that desmopressin could not reduce the amount of blood loss after cabg. also, desmopressin did not have a significant effect on coagulation status. therefore, based on the results of our study, it seems that the use of this medication cannot be a helpful for patients with any indication for cabg. background coronary artery bypass grafting (cabg) is a common surgical...