This case report describes a patient with a history of epileptic seizures who showed unusual decreases in the Bispectral Index (BIS) attributable to the induction of abnormal slow electroencephalographic (EEG) waves by photic stimulation, without any associated decrease in his level of consciousness. After starting anticonvulsive therapy, photic stimulation no longer induced abnormal EEG activi...

A patient undergoing general anaesthesia for neurosurgery exhibited an unexpected sudden decrease in the BiSpectral Index (BIS) value to near-zero. This prompted the detection of profound hypotension using non-invasive blood pressure (NIBP) measurement and expedited urgent assessment and treatment, with the patient making a full recovery. Widely regarded as a 'depth of anaesthesia' monitor, thi...

BACKGROUND AND OBJECTIVES The bispectral index (BIS) is a multifactorial parameter derived from the electroencephalogram (EEG), which allows monitoring of the hypnotic component of anesthesia. It was obtained from the algorithm based on the analysis of a large number of EEGs from volunteers and patients undergoing sedation and general anesthesia with different anesthetic agents. The use of BIS ...

Editor, We read with great interest the article by Prabhakar et al. [1] regarding the use of bispectral index (BIS) monitoring for an elective frontal craniotomy and fenestration in a 2-year-old boy with bilateral frontal lobe porencephalic cysts. During the procedure, the patient presented low preanaesthetic BIS values (39) that showed no significant change (between 30 and 40), despite a reduc...

Introduction: Previous studies have suggested that Bispectral Index (BIS) may be less reliable in detecting depth of anesthesia or sedation during use of certain anesthetics or sedatives. These studies suggest that depth of sedation as measured by BIS may be drug-dependent. To date, data related to the effects of sedative agent on BIS in children are limited due to small sample sizes and inclus...

UNLABELLED The bispectral index (BIS) has been developed in adults and correlates well with clinical hypnotic effects of anesthetics. We investigated whether BIS reflects clinical markers of hypnosis and demonstrates agent dose-responsiveness in infants and children. In an observational arm of this study, BIS values in children undergoing general anesthesia were observed and compared with simil...

BACKGROUND Bispectral Index (BIS) has been used to measure sedation depth. Ideally, to guide anesthetic management, range of BIS scores at different sedation levels should not overlap, and BIS should be independent of drug used. This study assessed ability of BIS to predict sedation depth between sevoflurane, propofol, and midazolam. Quality of recovery was also compared. METHODS Patients und...

We have compared the auditory evoked potential index (AEPIndex) and bispectral index (BIS) for monitoring depth of anaesthesia in spontaneously breathing surgical patients. Twenty patients (aged 17-49 yr) undergoing day surgery were anaesthetized with computer-controlled infusions of propofol. The mean (SD and range) of each measurement was determined during consciousness and unconsciousness an...

OBJECTIVE Aminophylline, which is clinically used as a bronchodilator, antagonizes the action of adenosine, so it can be used to shorten the recovery time after general anesthesia. Therefore, we wanted to test the hypothesis that the administration of aminophylline leads to an increase in bispectral index (BIS) and clinical recovery in patients anesthetized with total intravenous anesthesia (TI...

BACKGROUNDS AND OBJECTIVE Some studies have shown that deeper anesthesia is more effective on postoperative analgesia and reduces the need for sedative drugs. This study sought to investigate the effect of depth of anesthesia on postoperative pain in laparoscopic cholecystectomy. MATERIALS AND METHODS In this double-blind clinical trial, 60 patients undergoing laparoscopic cholecystectomy wer...