OBJECTIVE Self-mutilation has traditionally been associated with borderline personality disorder, and seldom examined separately from suicide attempts. Clinical experience suggests that self-mutilation is common in bipolar disorder. METHODS A family study was conducted on the molecular genetics of depression and personality, in which the proband had been treated for depression. All probands a...

BACKGROUND This study aims to establish if adult patients with major depressive disorder (MDD) and childhood Attention Deficit/Hyperactivity disorder (ADHD) symptoms would be more frequently within the bipolar spectrum than depressed patients without childhood ADHD. METHODS This study was carried out in outpatients recruited by psychiatrists in private practice, with 3963 participants being i...

OBJECTIVE This study aimed to investigate relationships among temperament-character traits, dysfunctional attitudes and automatic thoughts, and compare with patient group with diagnosis of Major Depressive Disorder (MDD) and healthy control group in terms of these variables. METHOD 127 patients with a diagnosis of major depressive disorder and 128 healthy subjects participated voluntarily in ...

background non-diagnosed depression might postpone the physical healing of patients and negatively affects prognosis. the rate of major depressive disorder among patients of general practitioners in the united states reaches 10 percent and among patients admitted to the inner wards reaches 15 percent. patients and methods a cross sectional study on physician of two hospitals was performed. a qu...

BACKGROUND According to DSM-IV and ICD-10, hypomania which occurs solely during antidepressant treatment does not belong to the category of bipolar II (BP-II). METHODS As part of the EPIDEP National Multisite French Study of 493 consecutive DSM-IV major depressive patients evaluated in at least two semi-structured interviews 1 month apart, 144 (29.2%) fulfilled the criteria for bipolar II wit...

CONTEXT A variety of indirect evidence has implicated the central muscarinic-cholinergic system, and more specifically the type 2 muscarinic (M2) receptor, in the pathogenesis of depressive symptoms arising in major depressive disorder and bipolar disorder. OBJECTIVE To assess the binding potential of muscarinic2 receptors in vivo during depression in subjects with major depressive disorder o...

aim and background: major depressive disorder (mdd) is known to play a major role in the onset of coronary artery disease (cad). several studies demonstrated an association between dyslipidemia and mdd. the present study aimed to investigate the mean serum lipoproteins and apolipoprotein level in patients with mdd. method and materials: thirty-two patients, who fully met the fourth diagnostic a...